2. Gene
  3. Nrtn - neurturin Gene

Nrtn - neurturin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as NTN

Gene ID: 18188 | Gene type: protein coding

About Nrtn

Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. Homozygous knockout mice for this gene exhibit defects in the development of the retina and enteric nervous system, and reduced cholinergic innervation of the heart and lacrimal glands. [provided by RefSeq, Aug 2016]

Nrtn Products(1)

mRNA Protein Name
NM_008738.3 NP_032764.1 neurturin preproprotein
Protein Preferred Names Protein Names

neurturin

Recombinant Nrtn Proteins

Cat. No. Product Name Accession Purity
HY-P700224AF Animal-Free Neurturin Protein, Mouse (His) P97463.1 (P96-V195) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09582 NRTN Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nrtn NCBI NCBI:4902