2. Gene
  3. Tacr2 - tachykinin receptor 2 Gene

Tacr2 - tachykinin receptor 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Skr; Nk2r; Tac2r

Gene ID: 21337 | Gene type: protein coding

About Tacr2

Chromosome 10: 62,088,217-62,101,769 forward strand.GRCm39:CM001003.3

This gene has 1 transcript (splice variant), 200 orthologues, 55 paralogues and is associated with 2 phenotypes. Biased expression in adrenal adult (RPKM 85.1), colon adult (RPKM 9.6) and 1 other tissue.

Summary

Predicted to enable substance K receptor activity. Involved in regulation of uterine smooth muscle contraction. Predicted to be located in membrane; sperm flagellum; and sperm head. Predicted to be active in plasma membrane and sperm midpiece. Is expressed in adrenal gland. Human ortholog(s) of this gene implicated in asthma. Orthologous to human TACR2 (tachykinin receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Tacr2 Products(1)

mRNA Protein Name
NM_009314.4 NP_033340.3 substance-K receptor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in regulation of uterine smooth muscle contraction IDA
IDA: Inferred from direct assay
15647454 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Tacr2 Protein Structure

7tmA_SKR_NK2R

7tmA_SKR_NK2R: cd16004 (33 - 317)

7tmA_SKR_NK2R

7tmA_SKR_NK2R: cd16004 (34 - 60)

7tmA_SKR_NK2R

7tmA_SKR_NK2R: cd16004 (67 - 93)

7tmA_SKR_NK2R

7tmA_SKR_NK2R: cd16004 (105 - 135)

7tmA_SKR_NK2R

7tmA_SKR_NK2R: cd16004 (146 - 167)

7tmA_SKR_NK2R

7tmA_SKR_NK2R: cd16004 (193 - 222)

7tmA_SKR_NK2R

7tmA_SKR_NK2R: cd16004 (242 - 272)

7tmA_SKR_NK2R

7tmA_SKR_NK2R: cd16004 (285 - 310)

  • 0
  • 100
  • 200
  • 300
  • 384 a.a.
Protein Preferred Names Protein Names

substance-K receptor

7 transmembrane receptor

NK-2 receptor

NK-2R

neurokinin A receptor

tachykinin NK-2 receptor

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P3848 Tyr0-Neurokinin A Agonist / Unkown
HY-RS14146 TACR2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS14147 Tacr2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS14148 Tacr2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tacr2 NCBI NCBI:6865