Vnn1 - vanin 1 Gene

Mus musculus

Also known as V-1

Gene ID: 22361 | Gene type: protein coding

About Vnn1

Summary

Predicted to enable pantetheine hydrolase activity. Involved in several processes, including chronic inflammatory response; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; and positive regulation of T cell differentiation in thymus. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; facial bone primordium; genitourinary system; nervous system; and respiratory system. Orthologous to human VNN1 (vanin 1). [provided by Alliance of Genome Resources, Apr 2022]

Vnn1 Products(1)

mRNA	Protein	Name
NM_011704.3	NP_035834.2	pantetheinase precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables pantetheine hydrolase activity	IDA IDA: Inferred from direct assay	11042271	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in acute inflammatory response	IDA IDA: Inferred from direct assay	14966568	MGI
involved in cell-cell adhesion	IDA IDA: Inferred from direct assay	8934567	MGI
involved in chronic inflammatory response	IDA IDA: Inferred from direct assay	14966568	MGI
involved in coenzyme A catabolic process	IMP IMP: Inferred from mutant phenotype	11042271	MGI
involved in inflammatory response	IMP IMP: Inferred from mutant phenotype	15282320	MGI
involved in innate immune response	IDA IDA: Inferred from direct assay	14966568	MGI
involved in positive regulation of T cell differentiation in thymus	IDA IDA: Inferred from direct assay	8934567	MGI
involved in positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	IMP IMP: Inferred from mutant phenotype	15282320	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
NOT located in extracellular space	IDA IDA: Inferred from direct assay	11491533	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

pantetheinase

pantetheine hydrolase

vascular non-inflammatory molecule 1

Recombinant Vnn1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76126	VNN1/Vanin-1 Protein, Mouse (HEK293, Fc)	Q9Z0K8 (M1-S487)	≥95%
HY-P76127	VNN1/Vanin-1 Protein, Mouse (HEK293, His)	Q9Z0K8 (L24-N488)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15666	VNN1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Vnn1	NCBI	NCBI:8876

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