2. Gene
  3. Lrrtm4 - leucine rich repeat transmembrane neuronal 4 Gene

Lrrtm4 - leucine rich repeat transmembrane neuronal 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as A230052N11; 7530419J18Rik

Gene ID: 243499 | Gene type: protein coding

About Lrrtm4

Summary

Enables heparan sulfate proteoglycan binding activity. Involved in regulation of synapse assembly. Acts upstream of or within AMPA glutamate receptor clustering; positive regulation of synapse assembly; and regulation of presynaptic membrane organization. Located in glutamatergic synapse and postsynaptic membrane. Part of AMPA glutamate receptor complex. Is expressed in several structures, including central nervous system; embryo mesenchyme; and future midbrain. Orthologous to human LRRTM4 (leucine rich repeat transmembrane neuronal 4). [provided by Alliance of Genome Resources, Apr 2022]

Lrrtm4 Products(4)

mRNA Protein Name
NM_001134743.1 NP_001128215.1 leucine-rich repeat transmembrane neuronal protein 4 isoform 3 precursor
NM_001282102.1 NP_001269031.1 leucine-rich repeat transmembrane neuronal protein 4 isoform 2 precursor
NM_001347261.1 NP_001334190.1 leucine-rich repeat transmembrane neuronal protein 4 isoform 4 precursor
NM_178731.5 NP_848846.3 leucine-rich repeat transmembrane neuronal protein 4 isoform 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables heparan sulfate proteoglycan binding IDA
IDA: Inferred from direct assay
23911104 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within AMPA glutamate receptor clustering IMP
IMP: Inferred from mutant phenotype
23911104 MGI
acts upstream of or within neurotransmitter-gated ion channel clustering IDA
IDA: Inferred from direct assay
23911104 MGI
acts upstream of or within positive regulation of synapse assembly IDA
IDA: Inferred from direct assay
24613359 MGI
acts upstream of or within regulation of presynaptic membrane organization IDA
IDA: Inferred from direct assay
23911104 MGI
involved in regulation of synapse assembly IDA
IDA: Inferred from direct assay
23911103 MGI
involved in regulation of synapse assembly IMP
IMP: Inferred from mutant phenotype
23911103 MGI
Cellular Component GO Annotation Evidence Reference Source
part of AMPA glutamate receptor complex IDA
IDA: Inferred from direct assay
22632720 MGI
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
31974009 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
23911103 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
23911103 MGI
is active in photoreceptor ribbon synapse IDA
IDA: Inferred from direct assay
31974009 MGI
located in postsynaptic membrane IDA
IDA: Inferred from direct assay
23911104 MGI
is active in synapse IDA
IDA: Inferred from direct assay
31974009 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich repeat transmembrane neuronal protein 4

Recombinant Lrrtm4 Proteins

Cat. No. Product Name Accession Purity
HY-P77069 LRRTM4 Protein, Mouse (HEK293, His) Q80XG9-1 (Q31-K424) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07844 LRRTM4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lrrtm4 NCBI NCBI:80059