Junb - JunB proto-oncogene, AP-1 transcription factor subunit Gene

Rattus norvegicus

Gene ID: 24517 | Gene type: protein coding

About Junb

Summary

Enables DNA-binding transcription factor activity; double-stranded DNA binding activity; and sequence-specific DNA binding activity. Involved in several processes, including response to cAMP; response to steroid hormone; and transcription by RNA polymerase II. Located in nucleus. Biomarker of renal carcinoma. Orthologous to human JUNB (JunB proto-oncogene, AP-1 transcription factor subunit). [provided by Alliance of Genome Resources, Apr 2022]

Junb Products(1)

mRNA	Protein	Name
NM_021836.2	NP_068608.2	transcription factor JunB

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA binding	IDA IDA: Inferred from direct assay	12371906	RGD
enables DNA-binding transcription factor activity	IMP IMP: Inferred from mutant phenotype	10830307	RGD
enables double-stranded DNA binding	IDA IDA: Inferred from direct assay	10830307	RGD
enables sequence-specific DNA binding	IDA IDA: Inferred from direct assay	10830307	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to hormone stimulus	IEP IEP: Inferred from expression pattern	11460264	RGD
involved in cellular response to hypoxia	IEP IEP: Inferred from expression pattern	8593588	RGD
involved in female pregnancy	IEP IEP: Inferred from expression pattern	12080023	RGD
involved in response to 4-nitroquinoline N-oxide	IEP IEP: Inferred from expression pattern	14674993	RGD
involved in response to cAMP	IEP IEP: Inferred from expression pattern	18280640	RGD
involved in response to corticosterone	IEP IEP: Inferred from expression pattern	18485334	RGD
involved in response to cytokine	IEP IEP: Inferred from expression pattern	18280640	RGD
involved in response to light stimulus	IEP IEP: Inferred from expression pattern	11146118	RGD
involved in response to mechanical stimulus	IEP IEP: Inferred from expression pattern	15126239	RGD
involved in response to organic cyclic compound	IEP IEP: Inferred from expression pattern	10934195	RGD
involved in response to peptide hormone	IEP IEP: Inferred from expression pattern	10934195	RGD
involved in response to progesterone	IEP IEP: Inferred from expression pattern	12080023	RGD
involved in response to xenobiotic stimulus	IEP IEP: Inferred from expression pattern	12093589	RGD
involved in transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	10830307	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Junb Protein Structure

Jun

bZIP_Jun

0
100
200
300
344 a.a.

Protein Preferred Names

Protein Names

transcription factor JunB

Jun-B oncogene	jun B proto-oncogene
transcription factor AP-1 subunit JunB	transcription factor jun-B

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07057	JUNB Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS07058	Junb Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS07059	Junb Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Junb	NCBI	NCBI:3726

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