PLA2G4F - phospholipase A2 group IVF Gene

Homo sapiens

Also known as PLA2G4FZ

Gene ID: 255189 | Gene type: protein coding

About PLA2G4F

This gene has 7 transcripts (splice variants), 140 orthologues and 5 paralogues. Biased expression in skin (RPKM 54.3), lung (RPKM 12.6) and 6 other tissues.

Summary

Predicted to enable calcium ion binding activity; calcium-dependent Phospholipase A2 activity; and calcium-dependent phospholipid binding activity. Predicted to be involved in glycerophospholipid catabolic process. Predicted to act upstream of or within several processes, including arachidonic acid secretion; cellular response to antibiotic; and prostaglandin biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol; ruffle membrane; and vesicle. [provided by Alliance of Genome Resources, Apr 2022]

PLA2G4F Products(1)

mRNA	Protein	Name
NM_213600.4	NP_998765.3	cytosolic phospholipase A2 zeta precursor

PLA2G4F Protein Structure

PLA2_B

0
200
400
600
800
851 a.a.

Protein Preferred Names

Protein Names

cytosolic phospholipase A2 zeta

cPLA2-zeta

Related Diseases

Diseases

Alias

Mahvash Disease

Gcgr-Related Hyperglucagonemia	MVAH
Alpha-Cell Hyperplasia With Glucagonemia	Nesidioblastosis, Alpha Cell Hyperplasia, Microglucagonoma, And Nonfunctioning Islet Cell Tumor
Nesidioblastosis Alpha Cell Hyperplasia Microglucagonoma And Nonfunctioning Islet Cell Tumor

Inflammatory Bowel Disease 9

IBD9

Inflammatory Bowel Disease 1

Inflammatory Bowel Disease 1	IBD1
Crohn Disease-Associated Growth Failure	Crohn Disease
Regional Enteritis	Ulcerative Colitis
Crohn Disease-Associated Growth Failure, Susceptibility To	Inflammatory Bowel Disease 1, Crohn Disease
Bowel Disease, Inflammatory, Type 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10631	PLA2G4F Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	PLA2G4F	VGNC	VGNC:32962
Felis catus	PLA2G4F	VGNC	VGNC:64202
Canis familiaris	PLA2G4F	VGNC	VGNC:44629
Mus musculus	PLA2G4F	MGD	MGI:2685493
Rattus norvegicus	PLA2G4F	RGD	RGD:1593370
Macaca mulatta	PLA2G4F	VGNC	VGNC:76123

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