2. Gene
  3. Il2rb - interleukin 2 receptor subunit beta Gene

Il2rb - interleukin 2 receptor subunit beta Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as IL2RBC

Gene ID: 25746 | Gene type: protein coding

About Il2rb

Summary

Enables interleukin-2 binding activity and interleukin-2 receptor activity. Involved in cytokine-mediated signaling pathway and natural killer cell activation. Located in cell surface. Human ortholog(s) of this gene implicated in asthma; immunodeficiency 63; myasthenia gravis; and visceral leishmaniasis. Orthologous to human IL2RB (interleukin 2 receptor subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Il2rb Products(1)

mRNA Protein Name
NM_013195.2 NP_037327.2 interleukin-2 receptor subunit beta precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables interleukin-2 binding IMP
IMP: Inferred from mutant phenotype
1469024 RGD
enables interleukin-2 receptor activity IMP
IMP: Inferred from mutant phenotype
1469024 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cytokine-mediated signaling pathway IEP
IEP: Inferred from expression pattern
1889461 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
8898947 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-2 receptor subunit beta

IL-2 receptor subunit beta

IL-2R subunit beta

IL-2RB

P70-75

high affinity IL-2 receptor subunit beta

interleukin 2 receptor, beta chain

Recombinant Il2rb Proteins

Cat. No. Product Name Accession Purity
HY-P76771 IL-2R beta/CD122 Protein, Rat (HEK293, His) NP_037327 (A27-E239) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06749 IL2RB Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS16278 IL2RB Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990450 Anti-IL-2Rb/CD122 Antibody Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il2rb NCBI NCBI:3560
Canis familiaris Il2rb NCBI NCBI:403439
Macaca fascicularis Il2rb NCBI NCBI:102138714
Mus musculus Il2rb NCBI NCBI:16185
Macaca mulatta Il2rb NCBI NCBI:696331