2. Gene
  3. TRIM58 - tripartite motif containing 58 Gene

TRIM58 - tripartite motif containing 58 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as BIA2

Gene ID: 25893 | Gene type: protein coding

About TRIM58

This gene has 1 transcript (splice variant), 92 orthologues and 80 paralogues. Biased expression in bone marrow (RPKM 12.4), thyroid (RPKM 11.2) and 5 other tissues.

Summary

Predicted to enable dynein heavy chain binding activity; dynein intermediate chain binding activity; and ubiquitin protein Ligase activity. Predicted to be involved in several processes, including positive regulation of erythrocyte enucleation; protein ubiquitination; and regulation of nuclear migration along microtubule. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TRIM58 Products(1)

mRNA Protein Name
NM_015431.4 NP_056246.3 E3 ubiquitin-protein ligase TRIM58

TRIM58 Protein Structure

zf-C3HC4_4

zf-C3HC4_4: zinc finger of C3HC4-type, RING (16 - 60)

zf-B_box

zf-B_box: B-box zinc finger (93 - 132)

PRY

PRY: SPRY-associated domain (293 - 341)

SPRY

SPRY: SPRY domain (343 - 450)

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  • 486 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase TRIM58

RING-type E3 ubiquitin transferase TRIM58

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15058 TRIM58 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus TRIM58 MGD MGI:2684862
Canis familiaris TRIM58 VGNC VGNC:47828
Macaca mulatta TRIM58 VGNC VGNC:100177
Rattus norvegicus TRIM58 RGD RGD:1566174
Bos taurus TRIM58 VGNC VGNC:36343
Felis catus TRIM58 VGNC VGNC:66546