2. Gene
  3. HINFP - histone H4 transcription factor Gene

HINFP - histone H4 transcription factor Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as MIZF; HiNF-P; ZNF743

Gene ID: 25988 | Gene type: protein coding

About HINFP

Cytogenetic location: 11q23.3 Genomic coordinates (GRCh38): 11:119,121,580-119,136,059 (from NCBI)

This gene has 14 transcripts (splice variants) and 206 orthologues. Ubiquitous expression in testis (RPKM 6.2), lymph node (RPKM 4.3) and 25 other tissues.

Summary

This gene encodes a transcription factor that interacts with methyl-CpG-binding protein-2 (MBD2), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repression. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Aug 2011]

HINFP Products(17)

mRNA Protein Name
NM_001243259.2 NP_001230188.1 histone H4 transcription factor isoform 2
NM_001351957.2 NP_001338886.1 histone H4 transcription factor isoform 3
NM_001351958.2 NP_001338887.1 histone H4 transcription factor isoform 1
NM_001351959.2 NP_001338888.1 histone H4 transcription factor isoform 1
NM_001351960.2 NP_001338889.1 histone H4 transcription factor isoform 1
NM_001351961.2 NP_001338890.1 histone H4 transcription factor isoform 4
NM_001351962.2 NP_001338891.1 histone H4 transcription factor isoform 4
NM_001351963.2 NP_001338892.1 histone H4 transcription factor isoform 5
NM_001351964.2 NP_001338893.1 histone H4 transcription factor isoform 5
NM_001351965.2 NP_001338894.1 histone H4 transcription factor isoform 6
NM_001351966.2 NP_001338895.1 histone H4 transcription factor isoform 6
NM_001351969.2 NP_001338898.1 histone H4 transcription factor isoform 6
NM_001351971.2 NP_001338900.1 histone H4 transcription factor isoform 6
NM_001351972.2 NP_001338901.1 histone H4 transcription factor isoform 6
NM_001351974.2 NP_001338903.1 histone H4 transcription factor isoform 6
NM_015517.5 NP_056332.2 histone H4 transcription factor isoform 1
NM_198971.3 NP_945322.1 histone H4 transcription factor isoform 1

HINFP Protein Structure

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (186 - 210)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (229 - 251)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (255 - 278)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (345 - 368)

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  • 517 a.a.
Protein Preferred Names Protein Names

histone H4 transcription factor

MBD2 (methyl-CpG-binding protein)-interacting zinc finger protein

Related Diseases

Diseases Alias
Cerebrooculofacioskeletal Syndrome 2

COFS2

Cerebro-Oculo-Facio-Skeletal Syndrome 2

Cofs Syndrome
Fetal Alcohol Spectrum Disorder

Fetal Alcohol Spectrum Disorders

Fetal Alcohol Syndrome
Non-Syndromic X-Linked Intellectual Disability

X-Linked Non-Syndromic Intellectual Disability

Non-Specific X-Linked Mental Retardation

X-Linked Non-Specific Intellectual Disability
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06175 HINFP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus HINFP RGD RGD:1311492
Canis familiaris HINFP VGNC VGNC:50633
Mus musculus HINFP MGD MGI:2429620
Macaca mulatta HINFP VGNC VGNC:73408
Bos taurus HINFP VGNC VGNC:50615
Felis catus HINFP VGNC VGNC:62816