2. Gene
  3. SCG3 - secretogranin III Gene

SCG3 - secretogranin III Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SGIII

Gene ID: 29106 | Gene type: protein coding

About SCG3

Cytogenetic location: 15q21.2 Genomic coordinates (GRCh38): 15:51,681,503-51,721,026 (from NCBI)

This gene has 3 transcripts (splice variants) and 203 orthologues. Biased expression in brain (RPKM 94.6), adrenal (RPKM 8.5) and 1 other tissue.

Summary

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active Peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

SCG3 Products(2)

mRNA Protein Name
NM_001165257.2 NP_001158729.1 secretogranin-3 isoform 2
NM_013243.4 NP_037375.2 secretogranin-3 isoform 1 precursor

SCG3 Protein Structure

SGIII

SGIII: Secretogranin-3 (17 - 468)

  • 0
  • 100
  • 200
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  • 400
  • 468 a.a.
Protein Preferred Names Protein Names

secretogranin-3

Recombinant SCG3 Proteins

Cat. No. Product Name Accession Purity
HY-P71279 SCG3/Secretogranin-3 Protein, Human (449a.a, HEK293, His) Q8WXD2-1 (F20-L468) ≥95%
HY-P74568 SCG3/Secretogranin-3 Protein, Human (468a.a, HEK293, His,solution) Q8WXD2-1 (F20-L468) ≥95%

Related Diseases

Diseases Alias
Motility-Related Diarrhea
Exudative Vitreoretinopathy 1

Retinopathy Of Prematurity

Retrolental Fibroplasia

EVR1

Criswick-Schepens Syndrome

Rop

Exudative Vitreoretinopathy, Familial, Autosomal Dominant

Fevr, Autosomal Dominant

Premature Retinopathy

Vitreoretinopathy, Exudative 1

Autosomal Dominant Familial Exudative Vitreoretinopathy

Fevr

Vitreoretinopathy, Exudative, Type 1

Retinopathy Of Prematurity Nos

Rlf- [Retrolental Fibroplasia]

Rop - [Retinopathy Of Prematurity]

Terry Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12502 SCG3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SCG3 VGNC VGNC:34333
Canis familiaris SCG3 VGNC VGNC:45906
Rattus norvegicus SCG3 RGD RGD:621209
Mus musculus SCG3 MGD MGI:103032
Macaca mulatta SCG3 VGNC VGNC:77013
Felis catus SCG3 VGNC VGNC:64909
Macaca fascicularis SCG3 NCBI NCBI:101925820
Others SCG3 NCBI