2. Gene
  3. P2RX7 - purinergic receptor P2X 7 Gene

P2RX7 - purinergic receptor P2X 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 29665 | Gene type: protein coding

About P2RX7

Primary_assembly 12: 33,879,745-33,934,619 reverse strand.mRatBN7.2:CM026985.1

This gene has 6 transcripts (splice variants), 195 orthologues, 6 paralogues and is associated with 9 phenotypes. Biased expression in Liver (RPKM 74.), Lung (RPKM 67.2) and 9 other tissues.

Summary

Enables several functions, including ATP binding activity; extracellularly ATP-gated cation channel activity; and metal ion binding activity. Involved in several processes, including ATP export; bleb assembly; and positive regulation of macromolecule metabolic process. Located in several cellular components, including bleb; membrane raft; and terminal bouton. Is integral component of nuclear inner membrane. Part of protein-containing complex. Orthologous to human P2RX7 (purinergic receptor P2X 7). [provided by Alliance of Genome Resources, Apr 2022]

P2RX7 Products(1)

mRNA Protein Name
NM_019256.2 NP_062129.1 P2X purinoceptor 7

P2RX7 Protein Structure

P2X_receptor

P2X_receptor: pfam00864 (10 - 412)

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  • 619 a.a.
Protein Preferred Names Protein Names

P2X purinoceptor 7

ATP receptor

P2X purinoceptor 7-like

P2X7 purinoceptor

P2Z receptor

purinergic receptor P2X, ligand-gated ion channel, 7

purinergic receptor P2X7

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09911 P2RX7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS09912 P2rx7 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS09913 P2RX7 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens P2RX7 NCBI NCBI:5027