2. Gene
  3. Dyrk3 - dual specificity tyrosine phosphorylation regulated kinase 3 Gene

Dyrk3 - dual specificity tyrosine phosphorylation regulated kinase 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 304775 | Gene type: protein coding

About Dyrk3

Primary_assembly 13: 42,594,121-42,604,778 reverse strand.mRatBN7.2:CM026986.1

This gene has 1 transcript (splice variant), 201 orthologues, 11 paralogues and is associated with 3 phenotypes. Biased expression in Testes (RPKM 172.1), Spleen (RPKM 69.1) and 4 other tissues.

Summary

Predicted to enable ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including nuclear speck organization; protein phosphorylation; and regulation of intracellular signal transduction. Predicted to be located in several cellular components, including cytoplasmic stress granule; nuclear speck; and pericentriolar material. Predicted to be active in cytoplasm; cytoskeleton; and nucleus. Orthologous to human DYRK3 (dual specificity tyrosine phosphorylation regulated kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Dyrk3 Products(1)

mRNA Protein Name
NM_001024767.1 NP_001019938.1 dual specificity tyrosine-phosphorylation-regulated kinase 3

Dyrk3 Protein Structure

PKc_DYRK2_3

PKc_DYRK2_3: cd14224 (141 - 520)

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  • 586 a.a.
Protein Preferred Names Protein Names

dual specificity tyrosine-phosphorylation-regulated kinase 3

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-105309 GSK-626616 Inhibitor 99.77% Unkown
HY-162750 ZJCK-6-46 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dyrk3 NCBI NCBI:8444