2. Gene
  3. LINGO4 - leucine rich repeat and Ig domain containing 4 Gene

LINGO4 - leucine rich repeat and Ig domain containing 4 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as LRRN6D; DAAT9248; PRO34002

Gene ID: 339398 | Gene type: protein coding

About LINGO4

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:151,800,264-151,805,419 (from NCBI)

This gene has 1 transcript (splice variant), 367 orthologues and 10 paralogues. Broad expression in adrenal (RPKM 1.2), testis (RPKM 0.4) and 16 other tissues.

Summary

Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be integral component of membrane. Predicted to be active in extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

LINGO4 Products(1)

mRNA Protein Name
NM_001004432.4 NP_001004432.1 leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4 precursor

LINGO4 Protein Structure

LRR_8

LRR_8: Leucine rich repeat (64 - 120)

LRR_8

LRR_8: Leucine rich repeat (157 - 212)

LRR_8

LRR_8: Leucine rich repeat (253 - 309)

I-set

I-set: Immunoglobulin I-set domain (420 - 501)

  • 0
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  • 500
  • 593 a.a.
Protein Preferred Names Protein Names

leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4

leucine-rich repeat neuronal protein 6D

Related Diseases

Diseases Alias
Essential Tremor

Benign Essential Tremor

Familial Tremor

Hereditary Essential Tremor

Essential Hereditary Tremor

Shaky Hand Syndrome

Benign Essential Tremor Syndrome

Tremor Hereditary Essential

Essential Tremor, Susceptibility To

Tremor, Hereditary Essential
Tremor, Hereditary Essential, 5

ETM5

Essential Tremor 5

Essential Tremor, Hereditary, 5

Hereditary Essential Tremor 5

Tremor, Hereditary Essential 5

Tremor, Essential Hereditary, Type 5
Tremor, Hereditary Essential, 4

ETM4

Essential Tremor 4

Essential Tremor, Hereditary, 4

Hereditary Essential Tremor 4

Tremor, Hereditary Essential 4

Tremor, Hereditary Essential, Type 4
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07683 LINGO4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus LINGO4 VGNC VGNC:63238
Bos taurus LINGO4 VGNC VGNC:30902
Mus musculus LINGO4 MGD MGI:2444651
Macaca mulatta LINGO4 VGNC VGNC:74171
Canis familiaris LINGO4 VGNC VGNC:42691
Rattus norvegicus LINGO4 RGD RGD:1562025