1. Gene
  2. Car12 - carbonic anhydrase 12 Gene

Car12 - carbonic anhydrase 12 Gene

Rattus norvegicus

Also known as Ca12

Gene ID: 363085 | Gene type: protein coding

About Car12

Primary_assembly 8: 67,274,359-67,330,440 forward strand.mRatBN7.2:CM026981.1

This gene has 3 transcripts (splice variants), 215 orthologues, 16 paralogues and is associated with 6 phenotypes.

Summary

Predicted to enable carbonate dehydratase activity. Predicted to be involved in chloride ion homeostasis and one-carbon metabolic process. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in isolated hyperchlorhidrosis. Orthologous to human CA12 (Carbonic Anhydrase 12). [provided by Alliance of Genome Resources, Apr 2022]

Car12 Products(1)

mRNA Protein Name
NM_001080756.2 NP_001074225.1 carbonic anhydrase 12 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in estrous cycle IEP
IEP: Inferred from expression pattern
23869188 RGD
Cellular Component GO Annotation Evidence Reference Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
23869188 RGD
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
12923247 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

carbonic anhydrase 12

carbonic anyhydrase 12

membrane-bound carbonic anhydrase 12