OMG - oligodendrocyte myelin glycoprotein Gene

Homo sapiens

Also known as OMGP

Gene ID: 4974 | Gene type: protein coding

About OMG

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:31,294,647-31,297,239 (from NCBI)

This gene has 4 transcripts (splice variants), 250 orthologues and 10 paralogues. Restricted expression toward brain (RPKM 57.3).

Summary

Predicted to enable identical protein binding activity. Predicted to be involved in neuron projection regeneration. Predicted to act upstream of or within regulation of collateral sprouting of intact axon in response to injury. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

OMG Products(1)

mRNA	Protein	Name
NM_002544.5	NP_002535.3	oligodendrocyte-myelin glycoprotein precursor

OMG Protein Structure

LRRNT

LRR_4

LRR_6

LRR_8

0
100
200
300
400
440 a.a.

Protein Preferred Names

Protein Names

oligodendrocyte-myelin glycoprotein

Recombinant OMG Proteins

Cat. No.	Product Name	Accession	Purity
HY-P75948	OMGP Protein, Human (HEK293, His)	P23515-1 (I25-P416)	≥95%

Related Diseases

Diseases

Alias

Neurofibromatosis, Type I

Von Recklinghausen Disease	Neurofibromatosis 1
Neurofibromatosis, Type 1	NF1
Neurofibromatosis, Peripheral Type	Neurofibromatosis Type I
Neurofibromatosis Type 1 Due To Nf1 Mutation Or Intragenic Deletion	Familial Spinal Neurofibromatosis
Fsnf	Peripheral Neurofibromatosis
Von Recklinghausen'S Neurofibromatosis	Von Recklinghausen Disease Due To Nf1 Mutation Or Intragenic Deletion
Neurofibromatosis Peripheral Type	Von Recklinghausen Syndrome
Neurofibromatosis Type 1	Von Recklinghausen Neuropathy
Nf1 - [Neurofibromatosis Type 1]	Recklinghausen Disease

Internuclear Ophthalmoplegia

Ophthalmoplegia Internuclearis	Bielschowsky-Lutz-Cogan Syndrome
Ino - [Internuclear Ophthalmoplegia]	Lhermitte Syndrome
Mlf - [Medial Longitudinal Fasciculus] Syndrome	Internuclear Paralysis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-N6669	Methyl 3-O-methylgallate		99.73%	Unkown
HY-RS09783	OMG Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	OMG	VGNC	VGNC:75584
Mus musculus	OMG	MGD	MGI:106586
Bos taurus	OMG	VGNC	VGNC:50238
Felis catus	OMG	VGNC	VGNC:99315
Rattus norvegicus	OMG	RGD	RGD:1359125
Canis familiaris	OMG	VGNC	VGNC:49934
Susscrofa domestica	OMG	NCBI
Others	OMG	NCBI

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