P2RX5 - purinergic receptor P2X 5 Gene

Homo sapiens

Also known as P2X5; LRH-1; P2X5R

Gene ID: 5026 | Gene type: protein coding

About P2RX5

Cytogenetic location: 17p13.2 Genomic coordinates (GRCh38): 17:3,673,227-3,696,155 (from NCBI)

This gene has 12 transcripts (splice variants), 252 orthologues and 6 paralogues. Biased expression in lymph node (RPKM 41.6), spleen (RPKM 36.1) and 4 other tissues.

Summary

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream gene, TAX1BP3 (Tax1 binding protein 3). [provided by RefSeq, Mar 2011]

P2RX5 Products(4)

mRNA	Protein	Name
NM_001204519.2	NP_001191448.1	P2X purinoceptor 5 isoform D
NM_001204520.2	NP_001191449.1	P2X purinoceptor 5 isoform E
NM_002561.4	NP_002552.2	P2X purinoceptor 5 isoform A
NM_175080.3	NP_778255.1	P2X purinoceptor 5 isoform B

P2RX5 Protein Structure

P2X_receptor

0
100
200
300
422 a.a.

Protein Preferred Names

Protein Names

P2X purinoceptor 5

ATP receptor subunit

Related Diseases

Diseases

Alias

Infiltrative Basal Cell Carcinoma

Skin Infiltrating Basal Cell Carcinoma

Cystinosis

Cystine Storage Disease	Cystine Diathesis
Cystine Disease	Cystinoses
Protein Defect Of Cystin Transport	Cystin Transport, Protein Defect Of
Nephropathic Cystinosis	Protein Defect Of Cystine Transport

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09909	P2RX5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	P2RX5	RGD	RGD:620256
Mus musculus	P2RX5	MGD	MGI:2137026

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