CALHM2 - calcium homeostasis modulator family member 2 Gene

Homo sapiens

Also known as FAM26B

Gene ID: 51063 | Gene type: protein coding

About CALHM2

Cytogenetic location: 10q24.33 Genomic coordinates (GRCh38): 10:103,446,786-103,452,370 (from NCBI)

This gene has 7 transcripts (splice variants), 180 orthologues and 5 paralogues. Ubiquitous expression in ovary (RPKM 19.8), endometrium (RPKM 13.4) and 22 other tissues.

Summary

Predicted to enable cation channel activity. Involved in positive regulation of apoptotic process. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

CALHM2 Products(1)

mRNA	Protein	Name
NM_015916.5	NP_057000.2	calcium homeostasis modulator protein 2

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in ATP export	IDA IDA: Inferred from direct assay	32832629	GOA
involved in positive regulation of apoptotic process	IDA IDA: Inferred from direct assay	16751333	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CALHM2 Protein Structure

Ca_hom_mod

0
100
200
300
323 a.a.

Protein Preferred Names

Protein Names

calcium homeostasis modulator protein 2

calcium homeostasis modulator 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01838	CALHM2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CALHM2	MGD	MGI:1919941
Rattus norvegicus	CALHM2	RGD	RGD:1308276
Canis familiaris	CALHM2	VGNC	VGNC:38668
Felis catus	CALHM2	VGNC	VGNC:60324
Macaca mulatta	CALHM2	VGNC	VGNC:70614
Bos taurus	CALHM2	VGNC	VGNC:26708

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