2. Gene
  3. HECA - hdc homolog, cell cycle regulator Gene

HECA - hdc homolog, cell cycle regulator Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HDC; HDCL; HHDC; dJ225E12.1

Gene ID: 51696 | Gene type: protein coding

About HECA

Cytogenetic location: 6q24.1 Genomic coordinates (GRCh38): 6:139,135,080-139,180,802 (from NCBI)

This gene has 1 transcript (splice variant) and 205 orthologues. Ubiquitous expression in lymph node (RPKM 16.9), spleen (RPKM 16.5) and 25 other tissues.

Summary

This gene encodes the homolog of the Drosophila headcase protein, a highly basic, cytoplasmic protein that regulates the re-entry of imaginal cells into the mitotic cycle during adult morphogenesis. In Drosophila, the encoded protein also inhibits terminal branching of neighboring cells during tracheal development. [provided by RefSeq, Jul 2008]

HECA Products(1)

mRNA Protein Name
NM_016217.3 NP_057301.1 headcase protein homolog
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of mitotic cell cycle IDA
IDA: Inferred from direct assay
19643820 GOA
involved in negative regulation of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
22100912 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
19643820 GOA
located in nucleus IDA
IDA: Inferred from direct assay
19643820 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HECA Protein Structure

HECA

HECA: Headcase protein family homologue (94 - 191)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 543 a.a.
Protein Preferred Names Protein Names

headcase protein homolog

headcase homolog

Related Diseases

Diseases Alias
Lichen Nitidus

Pinkus' Disease
Venous Hemangioma
Parapsoriasis

Digitate Dermatosis

Parapsoriasis En Plaque

Parapsoriasis En Plaques
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06106 HECA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus HECA VGNC VGNC:102438
Macaca mulatta HECA VGNC VGNC:73207
Mus musculus HECA MGD MGI:2685715
Rattus norvegicus HECA RGD RGD:1304818
Bos taurus HECA VGNC VGNC:29799
Canis familiaris HECA VGNC VGNC:41641