2. Gene
  3. TMEM214 - transmembrane protein 214 Gene

TMEM214 - transmembrane protein 214 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 54867 | Gene type: protein coding

About TMEM214

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:27,032,965-27,041,694 (from NCBI)

This gene has 13 transcripts (splice variants) and 200 orthologues. Ubiquitous expression in placenta (RPKM 25.1), thyroid (RPKM 23.8) and 25 other tissues.

Summary

Predicted to be involved in apoptotic process. Located in several cellular components, including Golgi apparatus; cytoplasmic microtubule; and endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

TMEM214 Products(2)

mRNA Protein Name
NM_001083590.2 NP_001077059.1 transmembrane protein 214 isoform 2
NM_017727.5 NP_060197.4 transmembrane protein 214 isoform 1
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasmic microtubule IDA
IDA: Inferred from direct assay
23264731 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM214 Protein Structure

TMEM214

TMEM214: TMEM214, C-terminal, caspase 4 activator (217 - 684)

  • 0
  • 200
  • 400
  • 600
  • 689 a.a.
Protein Preferred Names Protein Names

transmembrane protein 214

Related Diseases

Diseases Alias
Myopathy, X-Linked, With Postural Muscle Atrophy

Emery-Dreifuss Muscular Dystrophy 6, X-Linked

XMPMA

X-Linked Myopathy With Postural Muscle Atrophy

X-Linked Emery-Dreifuss Muscular Dystrophy 6

EDMD6

Emd6
Emery-Dreifuss Muscular Dystrophy 7, Autosomal Dominant

EDMD7

Autosomal Dominant Emery-Dreifuss Muscular Dystrophy 7

Emery-Dreifuss Muscular Dystrophy 7, Ad

Emd7

Dystrophy, Muscular, Emery-Dreifuss, Type 7, Autosomal Dominant
Emery-Dreifuss Muscular Dystrophy 5, Autosomal Dominant

EDMD5

Autosomal Dominant Emery-Dreifuss Muscular Dystrophy 5

Emd5

Dystrophy, Muscular, Emery-Dreifuss, Type 5, Autosomal Dominant
Emery-Dreifuss Muscular Dystrophy 4, Autosomal Dominant

EDMD4

Emery-Dreifuss Muscular Dystrophy 4 With Variable Features

Autosomal Dominant Emery-Dreifuss Muscular Dystrophy 4

Emd4

Dystrophy, Muscular, Emery-Dreifuss, Type 4, Autosomal Dominant

Emery-Dreifuss Muscular Dystrophy 4
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14698 TMEM214 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TMEM214 VGNC VGNC:36036
Rattus norvegicus TMEM214 RGD RGD:1311324
Macaca mulatta TMEM214 VGNC VGNC:103879
Canis familiaris TMEM214 VGNC VGNC:47532
Mus musculus TMEM214 MGD MGI:1916046
Felis catus TMEM214 VGNC VGNC:66311