1. Gene
  2. KIF16B - kinesin family member 16B Gene

KIF16B - kinesin family member 16B Gene

Homo sapiens

Also known as SNX23; C20orf23; KISC20ORF

Gene ID: 55614 | Gene type: protein coding

About KIF16B

Cytogenetic location: 20p12.1 Genomic coordinates (GRCh38): 20:16,272,104-16,573,448 (from NCBI)

This gene has 6 transcripts (splice variants), 166 orthologues and 41 paralogues. Ubiquitous expression in adrenal (RPKM 10.5), colon (RPKM 7.0) and 24 other tissues.

Summary

The protein encoded by this gene is a kinesin-like protein that may be involved in intracellular trafficking. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2010]

KIF16B Products(4)

mRNA Protein Name
NM_001199865.2 NP_001186794.1 kinesin-like protein KIF16B isoform 3
NM_001199866.2 NP_001186795.1 kinesin-like protein KIF16B isoform 1
NM_001410853.1 NP_001397782.1 kinesin-like protein KIF16B isoform 4
NM_024704.5 NP_078980.3 kinesin-like protein KIF16B isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables phosphatidylinositol-3,4,5-trisphosphate binding IDA
IDA: Inferred from direct assay
15882625 GOA
enables phosphatidylinositol-3,4-bisphosphate binding IDA
IDA: Inferred from direct assay
15882625 GOA
enables phosphatidylinositol-3,5-bisphosphate binding IDA
IDA: Inferred from direct assay
17641687 GOA
enables phosphatidylinositol-3-phosphate binding IDA
IDA: Inferred from direct assay
15882625 GOA
enables plus-end-directed microtubule motor activity IDA
IDA: Inferred from direct assay
15882625 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence Reference Source
involved in early endosome to late endosome transport IMP
IMP: Inferred from mutant phenotype
15882625 GOA
involved in epidermal growth factor receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
15882625 GOA
involved in receptor catabolic process IMP
IMP: Inferred from mutant phenotype
15882625 GOA
involved in regulation of receptor recycling IMP
IMP: Inferred from mutant phenotype
15882625 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
18445686 GOA
located in early endosome IDA
IDA: Inferred from direct assay
15882625 GOA
located in endosome IDA
IDA: Inferred from direct assay
17641687 GOA
located in spindle IDA
IDA: Inferred from direct assay
18445686 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KIF16B Protein Structure

Kinesin

Kinesin: Kinesin motor domain (9 - 358)

FHA

FHA: FHA domain (480 - 544)

PX

PX: PX domain (1197 - 1272)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1317 a.a.
Protein Preferred Names Protein Names

kinesin-like protein KIF16B

kinesin motor protein

Related Diseases

Diseases Alias
Congenital Fibrosis Of The Extraocular Muscles

Congenital Fibrosis Of Extraocular Muscles

Cfeom

Feom

Congenital External Ophthalmoplegia

Congenital Fibrosis Syndrome

General Fibrosis Syndrome

Megabladder, Congenital

MGBL

Congenital Megabladder

Small Intestine Neuroendocrine Neoplasm

Small Intestine Neuroendocrine Tumor

Neuroendocrine Tumor Of The Small Intestine

Net Of The Small Intestine

Neuroendocrine Neoplasm Of The Small Intestine

Neuroendocrine Tumor Of Small Bowel

Small Intestinal Neuroendocrine Neoplasm

Combined Oxidative Phosphorylation Deficiency 20

COXPD20

Combined Oxidative Phosphorylation Defect Type 20

Oxidative Phosphorylation Deficiency, Combined, Type 20

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Felis catus KIF16B VGNC VGNC:63105
Macaca mulatta KIF16B VGNC VGNC:73839
Rattus norvegicus KIF16B RGD RGD:1310146
Mus musculus KIF16B MGD MGI:1098240
Bos taurus KIF16B VGNC VGNC:30585
Canis familiaris KIF16B VGNC VGNC:42385