RAB20 - RAB20, member RAS oncogene family Gene

Homo sapiens

Gene ID: 55647 | Gene type: protein coding

About RAB20

This gene has 1 transcript (splice variant), 218 orthologues and 68 paralogues. Ubiquitous expression in spleen (RPKM 17.6), adrenal (RPKM 17.2) and 24 other tissues.

Summary

Predicted to enable GTPase activity. Involved in phagosome acidification and phagosome-lysosome fusion. Located in Golgi apparatus and phagocytic vesicle. [provided by Alliance of Genome Resources, Apr 2022]

RAB20 Products(1)

mRNA	Protein	Name
NM_017817.3	NP_060287.1	ras-related protein Rab-20

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
involved in phagosome acidification	IMP IMP: Inferred from mutant phenotype	21255211	GOA
involved in phagosome-lysosome fusion	IMP IMP: Inferred from mutant phenotype	21255211	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in phagocytic vesicle	IDA IDA: Inferred from direct assay	21255211	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RAB20 Protein Structure

Ras

0
100
200
234 a.a.

Protein Preferred Names

Protein Names

ras-related protein Rab-20

Related Diseases

Diseases

Alias

Laryngeal Tuberculosis

Tuberculosis, Laryngeal

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11530	RAB20 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	RAB20	VGNC	VGNC:45260
Felis catus	RAB20	VGNC	VGNC:97583
Bos taurus	RAB20	VGNC	VGNC:33627
Mus musculus	RAB20	MGD	MGI:102789
Rattus norvegicus	RAB20	RGD	RGD:1593487
Macaca mulatta	RAB20	VGNC	VGNC:106287

Name
Email *

	Sorry, but the email address you supplied was invalid.