C1orf112 - chromosome 1 open reading frame 112 Gene

Homo sapiens

Also known as Apolo1

Gene ID: 55732 | Gene type: protein coding

About C1orf112

This gene has 9 transcripts (splice variants) and 208 orthologues. Ubiquitous expression in testis (RPKM 5.7), lymph node (RPKM 3.2) and 24 other tissues.

C1orf112 Products(11)

mRNA	Protein	Name
NM_001320047.2	NP_001306976.1	uncharacterized protein C1orf112 isoform 1
NM_001320048.2	NP_001306977.1	uncharacterized protein C1orf112 isoform 2
NM_001320050.2	NP_001306979.1	uncharacterized protein C1orf112 isoform 3
NM_001320051.2	NP_001306980.1	uncharacterized protein C1orf112 isoform 4
NM_001363739.2	NP_001350668.1	uncharacterized protein C1orf112 isoform 5
NM_001366768.1	NP_001353697.1	uncharacterized protein C1orf112 isoform 6
NM_001366769.1	NP_001353698.1	uncharacterized protein C1orf112 isoform 7
NM_001366770.1	NP_001353699.1	uncharacterized protein C1orf112 isoform 8
NM_001366771.1	NP_001353700.1	uncharacterized protein C1orf112 isoform 5
NM_001366772.1	NP_001353701.1	uncharacterized protein C1orf112 isoform 5
NM_001366773.1	NP_001353702.1	uncharacterized protein C1orf112 isoform 5

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA
enables protein kinase binding	IDA IDA: Inferred from direct assay	34260926	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in chromosome segregation	IMP IMP: Inferred from mutant phenotype	34260926	GOA
involved in interstrand cross-link repair	IMP IMP: Inferred from mutant phenotype	37256941	GOA
involved in mitotic cell cycle	IMP IMP: Inferred from mutant phenotype	34260926	GOA
involved in regulation of protein kinase activity	IMP IMP: Inferred from mutant phenotype	34260926	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in chromosome, centromeric region	IDA IDA: Inferred from direct assay	34260926	GOA
located in kinetochore	IDA IDA: Inferred from direct assay	34260926	GOA
located in midbody	IDA IDA: Inferred from direct assay	34260926	GOA
located in nucleus	IDA IDA: Inferred from direct assay	34260926	GOA
located in spindle midzone	IDA IDA: Inferred from direct assay	34260926	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

C1orf112 Protein Structure

DUF4487

0
200
400
600
800
853 a.a.

Protein Preferred Names

Protein Names

uncharacterized protein C1orf112

associating protein with POLO1

Related Diseases

Diseases

Alias

Adiaspiromycosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01710	C1orf112 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	C1orf112	VGNC	VGNC:52639
Canis familiaris	C1orf112	VGNC	VGNC:52585
Macaca mulatta	C1orf112	VGNC	VGNC:70385
Mus musculus	C1orf112	MGD	MGI:3590554
Rattus norvegicus	C1orf112	RGD	RGD:1563470
Felis catus	C1orf112	VGNC	VGNC:60802

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