1. Gene
  2. TWSG1 - twisted gastrulation BMP signaling modulator 1 Gene

TWSG1 - twisted gastrulation BMP signaling modulator 1 Gene

Homo sapiens

Also known as TSG

Gene ID: 57045 | Gene type: protein coding

About TWSG1

Cytogenetic location: 18p11.22 Genomic coordinates (GRCh38): 18:9,334,773-9,402,420 (from NCBI)

This gene has 3 transcripts (splice variants) and 232 orthologues. Ubiquitous expression in endometrium (RPKM 35.8), gall bladder (RPKM 26.4) and 24 other tissues.

Summary

Enables transforming growth factor beta binding activity. Involved in several processes, including negative regulation of CD4-positive, alpha-beta T cell proliferation; positive regulation of pathway-restricted SMAD protein phosphorylation; and transforming growth factor beta receptor signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

TWSG1 Products(1)

mRNA Protein Name
NM_020648.6 NP_065699.1 twisted gastrulation protein homolog 1 precursor

TWSG1 Protein Structure

Tsg

Tsg: Twisted gastrulation (Tsg) protein conserved region (86 - 222)

  • 0
  • 100
  • 200
  • 223 a.a.
Protein Preferred Names Protein Names

twisted gastrulation protein homolog 1

twisted gastrulation homolog 1

Recombinant TWSG1 Proteins

Cat. No. Product Name Accession Purity
HY-P71391 TWSG1 Protein, Human (HEK293, His) Q9GZX9-1 (C26-F223) ≥95%

Related Diseases

Diseases Alias
Breast Intraductal Papillomatosis

Breast Papillomatosis

Intraductal Papillomatosis Of The Breast

Holoprosencephaly

Holoprosencephaly Sequence

Hpe

Hpe - [Holoprosencephaly]

Cataract 37

CTRCT37

Cca5

Cataract, Congenital, Cerulean Type, 5

Cataract 37, Autosomal Dominant

Congenital Cataract Cerulean Type 5

Prolapse Of Urethra

Urethrocele

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris TWSG1 VGNC VGNC:48004
Mus musculus TWSG1 MGD MGI:2137520
Felis catus TWSG1 VGNC VGNC:66718
Bos taurus TWSG1 VGNC VGNC:36528
Macaca mulatta TWSG1 VGNC VGNC:104255
Rattus norvegicus TWSG1 RGD RGD:1311215
Others TWSG1 NCBI