2. Gene
  3. PTGFRN - prostaglandin F2 receptor inhibitor Gene

PTGFRN - prostaglandin F2 receptor inhibitor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as FPRP; CD315; EWI-F; CD9P-1; SMAP-6

Gene ID: 5738 | Gene type: protein coding

About PTGFRN

Cytogenetic location: 1p13.1 Genomic coordinates (GRCh38): 1:116,909,916-116,990,353 (from NCBI)

This gene has 3 transcripts (splice variants), 227 orthologues and 5 paralogues. Ubiquitous expression in heart (RPKM 21.3), endometrium (RPKM 18.0) and 24 other tissues.

Summary

Predicted to be involved in myoblast fusion involved in skeletal muscle regeneration. Predicted to act upstream of or within lipid droplet organization. Located in cell surface. [provided by Alliance of Genome Resources, Apr 2022]

PTGFRN Products(1)

mRNA Protein Name
NM_020440.4 NP_065173.2 prostaglandin F2 receptor negative regulator precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
11278880 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PTGFRN Protein Structure

V-set

V-set: Immunoglobulin V-set domain (30 - 130)

Ig_2

Ig_2: Immunoglobulin domain (152 - 269)

V-set

V-set: Immunoglobulin V-set domain (283 - 376)

Ig_2

Ig_2: Immunoglobulin domain (417 - 528)

Ig_2

Ig_2: Immunoglobulin domain (562 - 659)

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  • 879 a.a.
Protein Preferred Names Protein Names

prostaglandin F2 receptor negative regulator

CD9 partner 1

Recombinant PTGFRN Proteins

Cat. No. Product Name Accession Purity
HY-P77467 FPRP/PTGFRN Protein, Cynomolgus (HEK293, His) H9ERH4 (R22-K830) ≥95%
HY-P77889 FPRP/PTGFRN Protein, Human (HEK293, His) Q9P2B2 (V26–P832) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11385 PTGFRN Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris PTGFRN VGNC VGNC:45148
Bos taurus PTGFRN VGNC VGNC:33508
Rattus norvegicus PTGFRN RGD RGD:3437
Macaca mulatta PTGFRN VGNC VGNC:76585
Felis catus PTGFRN VGNC VGNC:69144
Mus musculus PTGFRN MGD MGI:1277114
Macaca fascicularis PTGFRN NCBI NCBI:102120418
Others PTGFRN NCBI