AS3MT - arsenite methyltransferase Gene

Homo sapiens

Also known as CYT19

Gene ID: 57412 | Gene type: protein coding

About AS3MT

Cytogenetic location: 10q24.32 Genomic coordinates (GRCh38): 10:102,869,470-102,901,899 (from NCBI)

This gene has 1 transcript (splice variant), 190 orthologues and 4 paralogues. Biased expression in adrenal (RPKM 88.8), liver (RPKM 11.0) and 5 other tissues.

Summary

AS3MT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may play a role in arsenic metabolism (Lin et al., 2002 [PubMed 11790780]).[supplied by OMIM, Mar 2008]

AS3MT Products(1)

mRNA	Protein	Name
NM_020682.4	NP_065733.2	arsenite methyltransferase

AS3MT Protein Structure

Methyltransf_31

0
100
200
300
375 a.a.

Protein Preferred Names

Protein Names

arsenite methyltransferase

S-adenosyl-L-methionine:arsenic(III) methyltransferase

Related Diseases

Diseases

Alias

Borst-Jadassohn Intraepidermal Carcinoma

Intraepidermal Epithelioma Of Jadassohn

Bowen'S Disease, Clonal

Schizophrenia

SCZD	Schizophrenia With Or Without An Affective Disorder
Schizophrenia 12	Schizophrenia, Susceptibility To
Schizophrenia-1	Dementia Praecox
Schizophrenia 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01052	AS3MT Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	AS3MT	VGNC	VGNC:69856
Rattus norvegicus	AS3MT	RGD	RGD:621325
Bos taurus	AS3MT	VGNC	VGNC:97241
Felis catus	AS3MT	VGNC	VGNC:59951
Mus musculus	AS3MT	MGD	MGI:1929882

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