MYO1G - myosin IG Gene

Homo sapiens

Also known as HA2; MHAG; HLA-HA2

Gene ID: 64005 | Gene type: protein coding

About MYO1G

Cytogenetic location: 7p13 Genomic coordinates (GRCh38): 7:44,962,662-44,979,015 (from NCBI)

This gene has 8 transcripts (splice variants), 203 orthologues and 43 paralogues. Biased expression in bone marrow (RPKM 19.0), spleen (RPKM 14.5) and 9 other tissues.

Summary

MYO1G is a plasma membrane-associated class I Myosin (see MIM 601478) that is abundant in T and B lymphocytes and mast cells (Pierce et al., 2001 [PubMed 11544309]; Patino-Lopez et al., 2010 [PubMed 20071333]).[supplied by OMIM, Jun 2010]

MYO1G Products(1)

mRNA	Protein	Name
NM_033054.3	NP_149043.2	unconventional myosin-Ig

MYO1G Protein Structure

Myosin_head

Myosin_TH1

0
200
400
600
800
1018 a.a.

Protein Preferred Names

Protein Names

unconventional myosin-Ig

minor histocompatibility antigen HA-2

Related Diseases

Diseases

Alias

Graft-Versus-Host Disease

Graft-Versus-Host Disease, Susceptibility To	Graft Versus Host Disease
GVHDS	Graft-Versus-Host Disease, Protection Against
Gvh	Graft-Vs-Host Disease
Gvhd - [Graft-Versus-Host Disease]	Graft-Versus-Host Reaction Or Disease
Gvh - [Graft-Versus-Host] Disease	Gvh - [Graft-Versus-Host] Reaction

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08943	MYO1G Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	MYO1G	VGNC	VGNC:63687
Rattus norvegicus	MYO1G	RGD	RGD:1306016
Mus musculus	MYO1G	MGD	MGI:1927091
Bos taurus	MYO1G	VGNC	VGNC:31822
Macaca mulatta	MYO1G	VGNC	VGNC:74952

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