1. Gene
  2. CDH22 - cadherin 22 Gene

CDH22 - cadherin 22 Gene

Homo sapiens

Also known as C20orf25; dJ998H6.1

Gene ID: 64405 | Gene type: protein coding

About CDH22

Cytogenetic location: 20q13.12 Genomic coordinates (GRCh38): 20:46,173,739-46,308,498 (from NCBI)

This gene has 2 transcripts (splice variants), 197 orthologues and 33 paralogues. Biased expression in brain (RPKM 3.4), skin (RPKM 1.8) and 4 other tissues.

Summary

This gene is a member of the cadherin superfamily. The gene product is composed of five cadherin repeat domains and a cytoplasmic tail similar to the highly conserved cytoplasmic region of classical Cadherins. Expressed predominantly in the brain, this putative calcium-dependent cell adhesion protein may play an important role in morphogenesis and tissue formation in neural and non-neural cells during development and maintenance of the brain and neuroendocrine organs. [provided by RefSeq, Jul 2008]

CDH22 Products(1)

mRNA Protein Name
NM_021248.3 NP_067071.1 cadherin-22 precursor

CDH22 Protein Structure

Cadherin

Cadherin: Cadherin domain (71 - 158)

Cadherin

Cadherin: Cadherin domain (174 - 268)

Cadherin

Cadherin: Cadherin domain (282 - 363)

Cadherin

Cadherin: Cadherin domain (402 - 490)

Cadherin

Cadherin: Cadherin domain (503 - 600)

Cadherin_C

Cadherin_C: Cadherin cytoplasmic region (649 - 818)

  • 0
  • 200
  • 400
  • 600
  • 828 a.a.
Protein Preferred Names Protein Names

cadherin-22

PB-cadherin

Orthologs Information

Species Symbol Source ID
Canis familiaris CDH22 VGNC VGNC:39030
Macaca mulatta CDH22 VGNC VGNC:70940
Mus musculus CDH22 MGD MGI:1341843
Bos taurus CDH22 VGNC VGNC:27100
Felis catus CDH22 VGNC VGNC:60680
Rattus norvegicus CDH22 RGD RGD:2321