2. Gene
  3. ST3GAL2 - ST3 beta-galactoside alpha-2,3-sialyltransferase 2 Gene

ST3GAL2 - ST3 beta-galactoside alpha-2,3-sialyltransferase 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SIAT4B; ST3GALII; Gal-NAc6S; ST3GalA.2

Gene ID: 6483 | Gene type: protein coding

About ST3GAL2

Cytogenetic location: 16q22.1 Genomic coordinates (GRCh38): 16:70,375,977-70,439,100 (from NCBI)

This gene has 6 transcripts (splice variants), 204 orthologues and 14 paralogues. Ubiquitous expression in appendix (RPKM 6.9), spleen (RPKM 6.8) and 24 other tissues.

Summary

The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. This protein, which is a member of Glycosyltransferase family 29, can use the same acceptor substrates as does Sialyltransferase 4A. [provided by RefSeq, Jul 2008]

ST3GAL2 Products(1)

mRNA Protein Name
NM_006927.4 NP_008858.1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2

ST3GAL2 Protein Structure

Glyco_transf_29

Glyco_transf_29: Glycosyltransferase family 29 (sialyltransferase) (91 - 349)

  • 0
  • 100
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  • 300
  • 350 a.a.
Protein Preferred Names Protein Names

CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2

Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase

Related Diseases

Diseases Alias
Kidney Fibrosarcoma

Fibrosarcoma Of The Kidney
Salt And Pepper Syndrome

Salt & Pepper Syndrome

Salt-And-Pepper Syndrome
West Syndrome

Infantile Spasms

Infantile Spasms Syndrome

Infantile Spasm

X-Linked Infantile Spasm Syndrome

X-Linked Infantile Spasms

Epileptic Encephalopathy, Early Infantile, 1

Is

Tonic Spasms With Clustering, Arrest Of Psychomotor Development And Hypsarrhythmia On Eeg

West'S Syndrome

Spasms, Infantile

Is -[Infantile Spasm]

Salaam Spasm

Salaam Tic
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13847 ST3GAL2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ST3GAL2 VGNC VGNC:77826
Mus musculus ST3GAL2 MGD MGI:99427
Rattus norvegicus ST3GAL2 RGD RGD:68413
Felis catus ST3GAL2 VGNC VGNC:65720
Bos taurus ST3GAL2 VGNC VGNC:35332
Canis familiaris ST3GAL2 VGNC VGNC:46851