LGALS7B - galectin 7B Gene

Homo sapiens

Also known as PI7; GAL7; Gal-7; HKL-14; LGALS7

Gene ID: 653499 | Gene type: protein coding

About LGALS7B

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:38,789,200-38,791,754 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 328 orthologues and 16 paralogues. Restricted expression toward skin (RPKM 506.8).

Summary

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:3963) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008]

LGALS7B Products(1)

mRNA	Protein	Name
NM_001042507.4	NP_001035972.1	galectin-7

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LGALS7B Protein Structure

Gal-bind_lectin

0
100
136 a.a.

Protein Preferred Names

Protein Names

galectin-7

keratinocyte lectin 14

Recombinant LGALS7B Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70358	Galectin-7/LGALS7 Protein, Human	P47929 (M1-F136)	≥95%
HY-P73071	Galectin-7/LGALS7 Protein, Human (GST)	P47929 (S2-F136)	≥95%
HY-P700080AF	Animal-Free Galectin-7/LGALS7 Protein, Human (His)	P47929 (S2-F136)	≥95%

Related Diseases

Diseases

Alias

Esophageal Basaloid Squamous Cell Carcinoma

Basaloid Squamous Carcinoma Of Esophagus

Esophageal Basaloid Carcinoma

Galactosemia I

Galactosemia	Galt Deficiency
Classic Galactosemia	Galactose-1-Phosphate Uridylyltransferase Deficiency
Galactose-1-Phosphate Uridyltransferase Deficiency	GALAC1
Galactosemia, Classic	Galactosemia Type 1
Galactosemias	Classical Galactosemia
Galactosaemia	Galactose Intolerance
Epimerase Deficiency Galactosemia	Galactokinase Deficiency Disease
Galactose Epimerase Deficiency	Galactose-1-Phosphate Uridyl-Transferase Deficiency Disease
Gale Deficiency	Galk Deficiency
Udp-Galactose-4-Epimerase Deficiency Disease	Utp Hexose-1-Phosphate Uridylyltransferase Deficiency
Galactosemia 1	Galactosemia, Duarte Variant
Deficiency Of Galactokinase	Udpglucose 4-Epimerase Deficiency Disease
Classical Galactosaemia	Galput Deficiency - [Galactose-4-Phosphate Uridyltransferase] Deficiency
Classic Galactosaemia	Deficiency Of Hexose-1-Phosphate Uridylyltransferase
Deficiency Of Udpglucose-Hexose-1-Phosphate Uridylyltransferase	Deficiency Of Galactose-1-Phosphate Uridylyltransferase
Galactose-1-Phosphate Uridyl Transferase Deficiency	Transferase Deficiency Galactosemia
Deficiency Of Uridyl Transferase	Deficiency Of Utp-Hexose-1-Phosphate Uridylyltransferase
Utp-Hexose-1-Phosphate Uridyltransferase Deficiency

Bladder Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Bladder	Epidermoid Carcinoma Of The Urinary Bladder
Carcinoma Squamous Cell Bladder

Amyloid Tumor

Amyloid Neoplasm

Amyloid Tumour

Verruciform Xanthoma Of Skin

Verruciform Xanthoma

Cutaneous Verruciform Xanthoma

Fetal Adenoma

Microfollicular Adenoma

Uterus Carcinoma In Situ

Cervix Uteri Carcinoma In Situ

Carcinoma In Situ Of Cervix	Carcinoma In Situ Of Uterine Cervix
Cervical Intraepithelial Neoplasia	Carcinoma Of Cervix Stage 0
Cervical Intraepithelial Neoplasia Grade Iii With Severe Dysplasia	Cervix Ca In Situ
Cin Iii	Cin Iii - Carcinoma In Situ Of Cervix
Cin Iii - Severe Dyskaryosis	Severe Dysplasia Of Cervix
Severe Dysplasia Of The Cervix Uteri	Squamous Intraepithelial Neoplasia, Grade Iii
Cervix Intraepithelial Neoplasia Grade 3 Ajcc V7

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07608	LGALS7B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	LGALS7B	MGD	MGI:1316742

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