2. Gene
  3. SLCO2A1 - solute carrier organic anion transporter family member 2A1 Gene

SLCO2A1 - solute carrier organic anion transporter family member 2A1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PGT; MATR1; PHOAD; PHOAR2; OATP2A1; SLC21A2

Gene ID: 6578 | Gene type: protein coding

About SLCO2A1

Cytogenetic location: 3q22.1-q22.2 Genomic coordinates (GRCh38): 3:133,932,701-134,029,925 (from NCBI)

This gene has 8 transcripts (splice variants), 215 orthologues, 10 paralogues and is associated with 4 phenotypes. Broad expression in lung (RPKM 28.3), thyroid (RPKM 27.0) and 20 other tissues.

Summary

This gene encodes a prostaglandin transporter that is a member of the 12-membrane-spanning superfamily of transporters. The encoded protein may be involved in mediating the uptake and clearance of prostaglandins in numerous tissues. [provided by RefSeq, Dec 2011]

SLCO2A1 Products(1)

mRNA Protein Name
NM_005630.3 NP_005621.2 solute carrier organic anion transporter family member 2A1
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in basal plasma membrane IDA
IDA: Inferred from direct assay
35307651 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLCO2A1 Protein Structure

OATP

OATP: Organic Anion Transporter Polypeptide (OATP) family (31 - 603)

Kazal_2

Kazal_2: Kazal-type serine protease inhibitor domain (450 - 494)

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  • 643 a.a.
Protein Preferred Names Protein Names

solute carrier organic anion transporter family member 2A1

matrin F/G 1

Related Diseases

Diseases Alias
Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive, 2

PHOAR2

Pachydermoperiostosis, Autosomal Recessive

Pdp, Autosomal Recessive

Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2

Osteoarthropathy, Hypertrophic, Primary, Autosomal Recessive, Type 2
Hypertrophic Osteoarthropathy, Primary, Autosomal Dominant

PHOAD

Pho, Autosomal Dominant

Pachydermoperiostosis, Autosomal Dominant

Pdp, Autosomal Dominant
Chronic Enteropathy Associated With Slco2a1 Gene

Ceas
Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive, 1

Cranioosteoarthropathy

PHOAR1

Pachydermoperiostosis, Autosomal Recessive

Touraine-Solente-Gole Syndrome

Pho, Autosomal Recessive

Pdp, Autosomal Recessive

Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1

Cranio Osteoarthropathy

Cranio-Osteoarthropathy

Currarino Disease

Currarino Idiopathic Osteoarthropathy

Reginato-Schiapachasse Syndrome

Touraine-Solente-Golé Syndrome

COA

Pachydermoperiostosis Autosomal Recessive

Pdp Autosomal Recessive

Pho Autosomal Recessive

Osteoarthropathy, Hypertrophic, Primary, Autosomal Recessive, Type 1

Osteoarthropathy, Primary Hypertrophic

Reginato Schiapachasse Syndrome
Acromegaloid Changes, Cutis Verticis Gyrata, And Corneal Leukoma

Pachydermoperiostosis

Rosenthal-Kloepfer Syndrome

Pdp

Acromegaloid Changes, Cutis Verticis Gyrata And Corneal Leukoma

Idiopathic Hypertrophic Osteoarthropathy

Primary Hypertrophic Osteoarthropathy

Touraine Solente Gole Syndrome

Touraine-Solente-Gole Syndrome
Primary Hypertrophic Osteoarthropathy

Pachydermoperiostosis Syndrome

Osteoarthropathy, Primary Hypertrophic

Pachydermoperiostosis Of Nail

Idiopathic Hypertrophic Osteoarthropathy

Pho
Acroosteolysis

Acro-Osteolysis
Secondary Hypertrophic Osteoarthropathy

Osteoarthropathy, Secondary Hypertrophic

Bamberger-Marie Disease

Hpoa - Hypertrophic Pulmonary Osteoarthropathy

Hypertrophic Pulmonary Osteoarthropathy

Marie Bamberger Disease
Outlet Dysfunction Constipation
Ventriculomegaly With Cystic Kidney Disease

VMCKD

Cystic Kidney Disease With Ventriculomegaly

Ventriculomegaly-Cystic Kidney Disease

Ventriculomegaly - Cystic Kidney Disease

Congenital Nephrosis-Cerebral Ventriculomegaly Syndrome
Spinocerebellar Ataxia, Autosomal Recessive 6

SCAR6

Norwegian Infantile Onset Ataxia

Autosomal Recessive Spinocerebellar Ataxia 6

Autosomal Recessive Spinocerebellar Ataxia Type 6

Infantile-Onset Autosomal Recessive Nonprogressive Cerebellar Ataxia

Cerebellar Ataxia, Infantile Nonprogressive, Autosomal Recessive

Spinocerebellar Ataxia Autosomal Recessive 6

Cerebellar Ataxia Infantile Nonprogressive Autosomal Recessive
Hypokalemia

Potassium Deficiency

Potassium Deficiency Disorder

Hypopotassemia

Potassium

Potassium [K] Deficiency

Hypokalaemic Syndrome

Hypopotassaemia

Hypopotassaemia Syndrome

Hypokalaemic

Potassium Depletion
Congenital Heart Defects, Dysmorphic Facial Features, And Intellectual Developmental Disorder

CHDFIDD

Cdk13-Related Disorder

Cdk13-Related Chdfidd

Cdk13-Related Congenital Heart Defects, Dysmorphic Facial Features, Intellectual Developmental Disorder
Myelofibrosis

Primary Myelofibrosis

Agnogenic Myeloid Metaplasia

Idiopathic Myelofibrosis

Myeloid Metaplasia

Myelofibrosis With Myeloid Metaplasia

Osteomyelofibrosis

Megakaryocytic Myelosclerosis

Myelosclerosis

Chronic Idiopathic Myelofibrosis

Myelofibrosis, Idiopathic

Myelofibrosis With Myeloid Metaplasia, Somatic

Myelofibrosis, Somatic

Aleukemic Myelosis

Bone Marrow Fibrosis

MYELOF

MMM

Agnogenic Myeloid Metaplasia With Myelofibrosis

Ammm

Myelosclerosis With Myeloid Metaplasia

Myelofibrosis Nos
Intestinal Tuberculosis

Tuberculosis Of Intestine

Tuberculosis Of Intestines
Heart Disease

Heart Failure

Congenital Heart Disease

Heart Diseases

Congenital Heart Defects

Congenital Heart Defect

Heart Malformation

Congenital Anomaly Of Heart

Heart Defect

Heart-Congenital Defect

Congenital Heart Disorder

Heart Defects Congenital

Heart Defects, Congenital

Heart Defects

Heart Disease, Congenital

Disease, Heart, Congenital

Congestive Heart Failure
Osteogenesis Imperfecta, Type Iv

Osteogenesis Imperfecta Type 4

Osteogenesis Imperfecta Type Iv

OI4

Oi, Type Iv

Osteogenesis Imperfecta With Normal Sclerae

Oi Type Iv

Oi Type 4

Osteogenesis Imperfecta With Normal Sclera

Common Variable Oi With Normal Sclerae

Osteogenesis Imperfecta 4

Oi-Iv
Patent Ductus Arteriosus 1

Patent Ductus Arteriosus

PDA1

Pda

Ductus Arteriosus, Patent

Patent Ductus Arteriosus, Susceptibility To

Patent Ductus Botalli

Patency Of The Ductus Arteriosus

Patent Ductus Arteriosus Familial

Ductus Arteriosus Patent

Patent Ductus Arteriosus - Persisting Type
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13355 SLCO2A1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS13356 SLCO2B1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SLCO2A1 VGNC VGNC:77600
Felis catus SLCO2A1 VGNC VGNC:65444
Bos taurus SLCO2A1 VGNC VGNC:34951
Rattus norvegicus SLCO2A1 RGD RGD:3051
Canis familiaris SLCO2A1 VGNC VGNC:46495
Mus musculus SLCO2A1 MGD MGI:1346021