1. Gene
  2. TRAK2 - trafficking kinesin protein 2 Gene

TRAK2 - trafficking kinesin protein 2 Gene

Homo sapiens

Also known as GRIF1; MILT2; OIP98; CALS-C; GRIF-1; ALS2CR3

Gene ID: 66008 | Gene type: protein coding

About TRAK2

Cytogenetic location: 2q33.1 Genomic coordinates (GRCh38): 2:201,377,207-201,451,458 (from NCBI)

This gene has 5 transcripts (splice variants), 211 orthologues and 2 paralogues. Ubiquitous expression in heart (RPKM 26.1), thyroid (RPKM 23.5) and 25 other tissues.

Summary

Predicted to enable GABA Receptor binding activity and Myosin binding activity. Predicted to be involved in several processes, including mitochondrion distribution; organelle transport along microtubule; and protein targeting. Predicted to be located in cytoplasm and plasma membrane. Predicted to be active in cytoplasmic vesicle; dendrite; and mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

TRAK2 Products(1)

mRNA Protein Name
NM_015049.3 NP_055864.2 trafficking kinesin-binding protein 2

TRAK2 Protein Structure

HAP1_N

HAP1_N: HAP1 N-terminal conserved region (48 - 353)

Milton

Milton: Kinesin associated protein (413 - 567)

Milton

Milton: Kinesin associated protein (700 - 846)

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  • 914 a.a.
Protein Preferred Names Protein Names

trafficking kinesin-binding protein 2

O-linked N-acetylglucosamine transferase interacting protein 98

Related Diseases

Diseases Alias
Amyotrophic Lateral Sclerosis 2, Juvenile

ALS2

Als, Juvenile

Alsj

Amyotrophic Lateral Sclerosis Type 2

Amyotrophic Lateral Sclerosis 2

Amyotrophic Lateral Sclerosis Type 2, Juvenile

Amyotrophic Lateral Sclerosis Juvenile

Amyotrophic Lateral Sclerosis Juvenile 2

Sclerosis, Lateral, Amyotrophic, Type Type 2

Spinal Cord Lymphoma

Lymphoma Of The Spinal Cord

Spinal Cord Cancer

Spine Lymphoma

Spinal Cord--Cancer

Neuropathy, Congenital Hypomyelinating, 1, Autosomal Recessive

Charcot-Marie-Tooth Disease Type 4

Charcot-Marie-Tooth Disease Type 4e

Hereditary Motor And Sensory Neuropathy

Cmt4e

CHN1

Hypomyelinating Neuropathy, Congenital, 1

Charcot-Marie-Tooth Neuropathy Type 4e

Neuropathy, Congenital Hypomyelinating, 1

Ar-Cmt1

Autosomal Recessive Demyelinating Charcot-Marie-Tooth

Cmt4

Neuropathy, Congenital Hypomyelinating Or Amyelinating, Autosomal Recessive

Hypomyelination, Severe Congenital

Charcot-Marie-Tooth Disease, Type 4e

Charcot-Marie-Tooth Neuropathy, Type 4e

Autosomal Recessive Congenital Hypomyelinating Or Amyelinating Neuropathy

Autosomal Recessive Congenital Hypomyelinating Neuropathy

Congenital Amyelinating Neuropathy

Congenital Hypomyelinating Neuropathy Autosomal Recessive

Neuropathy, Congenital Hypomyelinating Or Amyelinating

Severe Congenital Hypomyelination

Hereditary Sensory Motor Neuropathy

Charcot-Marie-Tooth Disease, Demyelinating, Autosomal Recessive

Neuropathy, Hypomyelinating, Congenital, Type 1

Neuropathy, Motor And Sensory, Hereditary

Congenital Hypomyelinating Neuropathy

Hereditary Motor And Sensory Neuropathies

Hereditary Sensorimotor Neuropathy

Hmsn - [Hereditary Motor And Sensory Neuropathy]

Hsmn - [Hereditary Sensory And Motor Neuropathy]

Hereditary Motor And Sensory Neuropathy, Types I-Iv

Hereditary Spastic Paraplegia

Familial Spastic Paraplegia

Hereditary Spastic Paraparesis

Strumpell-Lorrain Disease

Familial Spastic Paraparesis

Hsp

Spg

Strümpell-Lorrain Disease

Spastic Paraplegia, Hereditary

French Settlement Disease

Strumpell-Lorrain Syndrome

Fsp

Spastic Paraplegia, Familial

Spastic Paraplegia Hereditary

Spastic Paraplegia 3, Autosomal Dominant

Spastic Paraparesis

Hereditary Spastic Paralysis

Familial Spastic Paralysis

Hereditary Spastic Ataxia

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Macaca mulatta TRAK2 VGNC VGNC:99413
Bos taurus TRAK2 VGNC VGNC:36281
Felis catus TRAK2 VGNC VGNC:66506
Mus musculus TRAK2 MGD MGI:1918077
Canis familiaris TRAK2 VGNC VGNC:47774
Rattus norvegicus TRAK2 RGD RGD:620915