1. Gene
  2. UGT2A3 - UDP glucuronosyltransferase family 2 member A3 Gene

UGT2A3 - UDP glucuronosyltransferase family 2 member A3 Gene

Homo sapiens
Gene ID: 79799 | Gene type: protein coding

About UGT2A3

Cytogenetic location: 4q13.2 Genomic coordinates (GRCh38): 4:68,928,463-68,951,804 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 1254 orthologues and 21 paralogues. Biased expression in duodenum (RPKM 93.7), small intestine (RPKM 88.2) and 5 other tissues.

Summary

Enables glucuronosyltransferase activity. Involved in cellular glucuronidation. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]

UGT2A3 Products(1)

mRNA Protein Name
NM_024743.4 NP_079019.3 UDP-glucuronosyltransferase 2A3 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables glucuronosyltransferase activity IDA
IDA: Inferred from direct assay
19858781 GOA
Biological Process GO Annotation Evidence Reference Source
involved in cellular glucuronidation IDA
IDA: Inferred from direct assay
19858781 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UGT2A3 Protein Structure

UDPGT

UDPGT: UDP-glucoronosyl and UDP-glucosyl transferase (24 - 521)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 527 a.a.
Protein Preferred Names Protein Names

UDP-glucuronosyltransferase 2A3

UDP glucuronosyltransferase 2 family, polypeptide A3

Related Diseases

Diseases Alias
Van Den Ende-Gupta Syndrome

VDEGS

Blepharophimosis, Arachnodactyly, And Congenital Contractures

Marden-Walker-Like Syndrome

Marden-Walker-Like Syndrome Without Psychomotor Retardation

Marden Walker Like Syndrome

Marden-Walker-Like Syndrome Without Psychmotor Retardation

Van Den Ende Gupta Syndrome

Marden Walker Like Syndrome Without Psychomotor Retardation

Blepharophimosis Arachnodactyly And Congenital Contractures

Crigler-Najjar Syndrome, Type I

Crigler-Najjar Syndrome

Crigler-Najjar Syndrome Type 1

Bilirubin Udp Glucuronyl Transferase Deficiency

Crigler Najjar Syndrome

Crigler Najjar Syndrome, Type 1

Bilirubin Uridinediphosphate Glucuronosyltransferase Deficiency

Bilirubin-Ugt Deficiency

Hyperbilirubinemia, Crigler-Najjar Type I

Hblrcn1

Familial Nonhemolytic Unconjugated Hyperbilirubinemia

Hereditary Unconjugated Hyperbilirubinemia

Bilirubin Uridinediphosphate Glucuronosyltransferase Deficiency Type 1

Bilirubin-Ugt Deficiency Type 1

Crigler-Najjar Syndrome 1

CN1

Cn-I

Crigler-Najjar Syndrome Type I

Hereditary Unconjugated Hyperbilirubinaemia

Ugt Deficiency

Bilirubin Glucuronosyltransferase Deficiency

Crigler-Najjar Disease Or Syndrome

Deficiency Of Glucuronosyltransferase

Glucuronyl Transferase Deficiency

Glucuronyltransferase Deficiency

Udp Glucuronyl Transferase Deficiency

Cns - [Crigler-Najjar Syndrome]

Congenital Familial Nonhemolytic Jaundice

Gilbert Syndrome

Gilbert Disease

Gilbert'S Disease

Gilbert'S Syndrome

Cholemia, Familial

Familial Nonhemolytic Jaundice

Meulengracht Syndrome

Gilbert Syndrome, Susceptibility To

Hyperbilirubinemia, Gilbert Type

Hblrg

Hyperbilirubinemia, Arias Type

Hyperbilirubinemia I

Constitutional Hyperbilirubinemia

Gilbert-Meulengracht Syndrome

Hereditary Nonhemolytic Jaundice

Hyperbilirubinemia Arias Type

Hyperbilirubinemia Type 1

Constitutional Liver Dysfunction

Gilbert-Lereboullet Syndrome

Hyperbilirubinemia 1

Unconjugated Benign Bilirubinemia

GILBS

Gilberts Syndrome

Familial Nonhaemolytic Jaundice

Constitutional Hyperbilirubinaemia

Hereditary Nonhaemolytic Bilirubinaemia

Familial Nonhaemolytic Bilirubinaemia

Idiopathic Hyperbilirubinaemia

Icterus Intermittens Juvenilis

Chronic Intermittent Juvenile Jaundice

Low-Grade Chronic Hyperbilirubinaemia Syndrome

Benign Unconjugated Bilirubinaemia Syndrome

Hereditary Nonhaemolytic Jaundice

Idiopathic Unconjugated Hyperbilirubinaemia

Gilbert--Lereboullet Syndrome

Constitutional Hepatic Dysfunction

Meulengracht Icterus

Cholaemia Familiaris Simplex

Familial Cholaemia

Congenital Familial Cholaemia

Physiologic Cholaemia

Hyperbilirubinaemia Type 1

Gilbert Cholaemia

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus UGT2A3 RGD RGD:1308444
Mus musculus UGT2A3 MGD MGI:1919344
Canis familiaris UGT2A3 VGNC VGNC:56079