MAP9 - microtubule associated protein 9 Gene

Homo sapiens

Also known as ASAP

Gene ID: 79884 | Gene type: protein coding

About MAP9

Cytogenetic location: 4q32.1 Genomic coordinates (GRCh38): 4:155,342,658-155,376,965 (from NCBI)

This gene has 9 transcripts (splice variants) and 188 orthologues. Broad expression in brain (RPKM 7.7), thyroid (RPKM 7.3) and 23 other tissues.

Summary

ASAP is a microtubule-associated protein required for spindle function, mitotic progression, and cytokinesis (Saffin et al., 2005 [PubMed 16049101]).[supplied by OMIM, Mar 2008]

MAP9 Products(1)

mRNA	Protein	Name
NM_001039580.2	NP_001034669.1	microtubule-associated protein 9

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables microtubule binding	IMP IMP: Inferred from mutant phenotype	16049101	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in mitotic spindle assembly	IDA IDA: Inferred from direct assay	16049101	GOA
involved in regulation of mitotic centrosome separation	IMP IMP: Inferred from mutant phenotype	16049101	GOA
involved in regulation of mitotic cytokinesis	IMP IMP: Inferred from mutant phenotype	16049101	GOA
involved in regulation of mitotic spindle organization	IMP IMP: Inferred from mutant phenotype	16049101	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in astral microtubule	IDA IDA: Inferred from direct assay	16049101	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	16049101	GOA
located in mitotic spindle	IDA IDA: Inferred from direct assay	16049101	GOA
located in spindle midzone	IDA IDA: Inferred from direct assay	16049101	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

microtubule-associated protein 9

aster-associated protein

Related Diseases

Diseases

Alias

Joubert Syndrome 7

JBTS7	Cerebello-Oculo-Renal Syndrome 3
Cors3	Joubert Syndrome, Type 7

Cone-Rod Dystrophy 6

CORD6	Retinal Cone Dystrophy 2
Rcd2	Dystrophy, Cone-Rod, Type 6
Retinitis Pigmentosa 6	Progressive Cone Degeneration
Cone Dystrophy

Cone-Rod Dystrophy 2

Cone-Rod Dystrophy	CORD2
Cone-Rod Retinal Dystrophy	Rcrd2
Cone-Rod Retinal Dystrophy 2	Crd2
Cord	Crd
Retinal Cone-Rod Dystrophy	Cone-Rod Retinal Dystrophy-2
Retinal Cone-Rod Dystrophy 2	Tapetoretinal Degeneration
Cone-Rod Degeneration	Cone Rod Dystrophy
Dystrophy, Cone-Rod	Dystrophy, Cone-Rod, Type 2
Retinitis Pigmentosa	Retinitis Pigmentosa 2
Progressive Cone-Rod Dystrophy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08091	MAP9 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	MAP9	VGNC	VGNC:103691
Macaca mulatta	MAP9	VGNC	VGNC:100244
Mus musculus	MAP9	MGD	MGI:2442208
Bos taurus	MAP9	VGNC	VGNC:31211
Felis catus	MAP9	VGNC	VGNC:107344
Rattus norvegicus	MAP9	RGD	RGD:1560368
Others	MAP9	NCBI

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