2. Gene
  3. RAB11FIP1 - RAB11 family interacting protein 1 Gene

RAB11FIP1 - RAB11 family interacting protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as RCP; NOEL1A; rab11-FIP1

Gene ID: 80223 | Gene type: protein coding

About RAB11FIP1

Cytogenetic location: 8p11.23 Genomic coordinates (GRCh38): 8:37,858,618-37,899,497 (from NCBI)

This gene has 6 transcripts (splice variants), 164 orthologues and 2 paralogues. Broad expression in lung (RPKM 41.1), small intestine (RPKM 24.3) and 22 other tissues.

Summary

This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including Integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013]

RAB11FIP1 Products(2)

mRNA Protein Name
NM_001002814.3 NP_001002814.2 rab11 family-interacting protein 1 isoform 3
NM_025151.5 NP_079427.4 rab11 family-interacting protein 1 isoform 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of adiponectin secretion IDA
IDA: Inferred from direct assay
24040321 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RAB11FIP1 Protein Structure

C2

C2: C2 domain (21 - 107)

RBD-FIP

RBD-FIP: FIP domain (1226 - 1273)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1200
  • 1283 a.a.
Protein Preferred Names Protein Names

rab11 family-interacting protein 1

RAB11 coupling protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11517 RAB11FIP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus RAB11FIP1 VGNC VGNC:33616
Felis catus RAB11FIP1 VGNC VGNC:64467
Macaca mulatta RAB11FIP1 VGNC VGNC:104491
Mus musculus RAB11FIP1 MGD MGI:1923017
Rattus norvegicus RAB11FIP1 RGD RGD:1562965