RAB11FIP1 - RAB11 family interacting protein 1 Gene

Homo sapiens

Also known as RCP; NOEL1A; rab11-FIP1

Gene ID: 80223 | Gene type: protein coding

About RAB11FIP1

Cytogenetic location: 8p11.23 Genomic coordinates (GRCh38): 8:37,858,618-37,899,497 (from NCBI)

This gene has 6 transcripts (splice variants), 164 orthologues and 2 paralogues. Broad expression in lung (RPKM 41.1), small intestine (RPKM 24.3) and 22 other tissues.

Summary

This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including Integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013]

RAB11FIP1 Products(2)

mRNA	Protein	Name
NM_001002814.3	NP_001002814.2	rab11 family-interacting protein 1 isoform 3
NM_025151.5	NP_079427.4	rab11 family-interacting protein 1 isoform 1

RAB11FIP1 Protein Structure

RBD-FIP

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1283 a.a.

Protein Preferred Names

Protein Names

rab11 family-interacting protein 1

RAB11 coupling protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11517	RAB11FIP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	RAB11FIP1	VGNC	VGNC:33616
Felis catus	RAB11FIP1	VGNC	VGNC:64467
Macaca mulatta	RAB11FIP1	VGNC	VGNC:104491
Mus musculus	RAB11FIP1	MGD	MGI:1923017
Rattus norvegicus	RAB11FIP1	RGD	RGD:1562965

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