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  2. H3C3 - H3 clustered histone 3 Gene

H3C3 - H3 clustered histone 3 Gene

Homo sapiens

Also known as H3.1; H3/c; H3C1; H3C2; H3C4; H3C6; H3C7; H3C8; H3FC; H3C10; H3C11; H3C12; HIST1H3C

Gene ID: 8352 | Gene type: protein coding

About H3C3

Cytogenetic location: 6p22.2 Genomic coordinates (GRCh38): 6:26,045,384-26,045,869 (from NCBI)

This gene has 1 transcript (splice variant), 70 orthologues and 20 paralogues.

Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]

H3C3 Products(1)

mRNA Protein Name
NM_003531.3 NP_003522.1 histone H3.1

H3C3 Protein Structure

Histone

Histone: Core histone H2A/H2B/H3/H4 (58 - 132)

  • 0
  • 100
  • 136 a.a.
Protein Preferred Names Protein Names

histone H3.1

H3 histone family, member C

Recombinant H3C3 Proteins

Cat. No. Product Name Accession Purity
HY-P72332 Histone H3 Protein, Human P68431 (A2-A136) ≥95%
HY-P72335 Histone H3 Protein, Human (98a.a, His) P68431 (P39-A136) ≥95%
HY-P72798 Histone H3 Protein, Human (His) P68431 (A2-A136) ≥95%

Related Diseases

Diseases Alias
Histone Mutated Tumor

Histone Mutated Tumour

Brain Stem Cancer

Brain Stem Neoplasms

Malignant Neoplasm Of Brain Stem

Malignant Neoplasm Of Brainstem

Neoplasm Of Adult Brain Stem

Neoplasm Of Brain Stem

Primary Brain Stem Neoplasm

Primary Brain Stem Tumor

Brain Stem Neoplasm

Brain Stem--Cancer

Brain Stem Neoplasms, Primary

Diffuse Midline Glioma, H3 K27m-Mutant

Diffuse Intrinsic Pontine Glioma

Dipg

Infiltrative Brainstem Glioma

Childhood Brain Stem Glioma

Pediatric Glioma Of The Brainstem

Hutchinson-Gilford Progeria Syndrome

Progeria

HGPS

Hutchinson-Gilford Syndrome

Hutchinson-Gilford Progeria

Hutchinson Gilford Syndrome

Hutchinson Gilford Progeria Syndrome

Hutchinson-Gilford Disease

Progeria Of Childhood

Hutchinson-Gilford-Progeria Syndrome

Adult Brainstem Astrocytoma

Adult Brain Stem Astrocytoma

Posterior Fossa Ependymoma
Clear Cell Chondrosarcoma

Chondrosarcoma, Clear Cell

Brain Stem Glioma

Brainstem Glioma

Brainstem Neuroglial Tumor

Glioma Of Brainstem

Spinal Cord Astrocytoma

Astrocytoma Of Spinal Cord

Spinal Astrocytoma

Spinal Cord Glioma

Glial Tumor Of Spinal Cord

Glial Neoplasm Spinal Cord

Glioma Of Spinal Cord

Anaplastic Pleomorphic Xanthoastrocytoma
Charcot-Marie-Tooth Disease, X-Linked Recessive, 3

CMTX3

Charcot-Marie-Tooth Disease X-Linked Recessive 3

Charcot-Marie-Tooth Neuropathy, X-Linked Recessive, 3

Cmt3x

X-Linked Charcot-Marie-Tooth Disease Type 3

Charcot-Marie-Tooth Neuropathy X-Linked Recessive 3

Charcot-Marie-Tooth Disease, X-Linked Type 3, Recessive

High Grade Ependymoma

Ependymal Neoplasm

Ependymal Tumors

Malignant Ependymoma

Ependymal Tumor

Anaplastic Ependymoma

Experimental Organism Malignant Ependymoma

Ependymoma Of Brain

Idh-Wildtype Glioblastoma
Astrocytoma, Idh-Mutant, Grade 4

Idh-Mutant Glioblastoma

Juvenile Pilocytic Astrocytoma
Diffuse Astrocytoma

Diffuse Astrocytoma, Low Grade

Who Grade Ii Astrocytoma

Fibrillary Astrocytoma

Gemistocytic Astrocytoma

Low-Grade Diffuse Astrocytoma

Protoplasmic Astrocytoma

Spinal Cancer

Spinal Cord Neoplasm

Spinal Cord Neoplasms

Spinal Neoplasms

Intraspinal Tumor

Malignant Tumor Of The Spinal Cord

Spinal Cord Cancer

Spinal Neoplasm

Tumor Of The Spinal Cord

Tumors Spinal Cord

Intraspinal Neoplasm

Spinal Cord--Cancer

Pilomyxoid Astrocytoma
Cerebral Ventricle Cancer

Cerebral Ventricle Neoplasms

Cerebral Ventricle Neoplasm

Intraventricular Tumor Of Brain

Supratentorial Ependymoma
Low Grade Glioma

Benign Glioma

Intracranial Cavernous Angioma

Intracranial Cavernoma

Intracranial Cavernous Hemangioma

Intracranial Structure Hemangioma

Angioma Of Intracranial Structure

Hemangioma Of Intracranial Structure

Hemangioma Of Intracranial Structures

Central Nervous System Benign Neoplasm

Benign Neoplasm Of The Central Nervous System

Pilocytic Astrocytoma

Juvenile Pilocytic Astrocytoma

Grade I Astrocytic Tumor

Piloid Astrocytoma

Atypical Teratoid Rhabdoid Tumor

Rhabdoid Tumor Predisposition Syndrome

Rtps

Atypical Teratoid/Rhabdoid Tumor

Rhabdoid Predisposition Syndrome

Familial Posterior Fossa Brain Tumor Of Infancy

Familial Rhabdoid Tumor

At/Rt

Atypical Teratoid Rhabdoid Tumour

Atypical Teratoid/Rhabdoid Tumour

Rhabdoid Tumor Of The Cns

Rhabdoid Tumour Of The Cns

Familial Posterior Fossa Brain Tumor Syndrome

Hereditary Swi/Snf Deficiency Syndrome

Atrt

Infratentorial Cancer

Infratentorial Neoplasms

Brain Neoplasm, Infratentorial

Malignant Infratentorial Tumors

Spinal Cord Disease

Spinal Cord Diseases

Myelopathy

Bone Marrow Diseases

Anaplastic Oligodendroglioma
Anaplastic Astrocytoma

Grade Iii Astrocytoma

Astrocytoma, Anaplastic

Grade Iii Astrocytic Tumor

Alpha-Thalassemia

Alpha Thalassemia

Alpha Thalassaemia

Alpha Plus Thalassemia

Thalassemia, Alpha-

Thalassemias, Alpha-

A-Thalassemia

Α-Thalassemia

A-THAL

Thalassemia

Alpha Thalassaemia Syndrome

Giant Cell Glioblastoma

Monstrocellular Sarcoma

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma