1. Gene
  2. SLC37A3 - solute carrier family 37 member 3 Gene

SLC37A3 - solute carrier family 37 member 3 Gene

Homo sapiens

Also known as SPX3

Gene ID: 84255 | Gene type: protein coding

About SLC37A3

Cytogenetic location: 7q34 Genomic coordinates (GRCh38): 7:140,333,752-140,398,530 (from NCBI)

This gene has 28 transcripts (splice variants), 295 orthologues and 12 paralogues. Ubiquitous expression in endometrium (RPKM 19.0), thyroid (RPKM 9.8) and 25 other tissues.

Summary

Predicted to enable transmembrane transporter activity. Predicted to be involved in carbohydrate transport and transmembrane transport. Is integral component of endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC37A3 Products(9)

mRNA Protein Name
NM_001287498.2 NP_001274427.1 sugar phosphate exchanger 3 isoform 3
NM_001363373.1 NP_001350302.1 sugar phosphate exchanger 3 isoform 4
NM_001363374.1 NP_001350303.1 sugar phosphate exchanger 3 isoform 5
NM_001363375.1 NP_001350304.1 sugar phosphate exchanger 3 isoform 6
NM_001363376.1 NP_001350305.1 sugar phosphate exchanger 3 isoform 7
NM_001363377.1 NP_001350306.1 sugar phosphate exchanger 3 isoform 8
NM_001363378.1 NP_001350307.1 sugar phosphate exchanger 3 isoform 9
NM_032295.4 NP_115671.1 sugar phosphate exchanger 3 isoform 2
NM_207113.3 NP_996996.1 sugar phosphate exchanger 3 isoform 1

SLC37A3 Protein Structure

MFS_1

MFS_1: Major Facilitator Superfamily (82 - 410)

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  • 494 a.a.
Protein Preferred Names Protein Names

sugar phosphate exchanger 3

solute carrier family 37 (glycerol-3-phosphate transporter), member 3

Related Diseases

Diseases Alias
Deafness, Autosomal Recessive 8

Neurosensory Nonsyndromic Recessive Deafness 8

DFNB8

Dfnb10

Deafness, Autosomal Recessive 10

Deafness, Childhood-Onset Neurosensory, Autosomal Recessive 8

Nsrd8

Autosomal Recessive Nonsyndromic Deafness 8

Deafness, Autosomal Recessive 8/10

Autosomal Recessive Deafness 10

Autosomal Recessive Deafness 8

Childhood-Onset Neurosensory Autosomal Recessive Deafness 8

Nrsd8

Deafness, Autosomal Recessive, 8

Childhood-Onset Neurosensory Deafness Autosomal Recessive 8

Deafness Autosomal Recessive 10

Deafness Autosomal Recessive 8/10

Deafness Neurosensory Autosomal Recessive 8

Non-Syndromic Neurosensory Deafness Autosomal Recessive Type 8

Non-Syndromic Sensorineural Deafness Autosomal Recessive Type 8

Deafness, Autosomal Recessive, Type 8/10

Caffey Disease

Infantile Cortical Hyperostosis

CAFYD

Cortical Congenital Hyperostosis

Caffey-Silverman Syndrome

De Toni-Caffey Disease

Hyperostosis Cortical Infantile

Hyperostosis, Cortical, Congenital

Glycerol Kinase Deficiency

Hyperglycerolemia

GKD

Gk Deficiency

Gk1 Deficiency

Deficiency Of Glycerol Kinase

Isolated Glycerol Kinase Deficiency

Glycerol Kinase Deficiency, Adult Form

Glycerol Kinase Deficiency, Juvenile Form

Deficiency, Glycerol Kinase

Glycogen Storage Disease Ia

Von Gierke Disease

Glycogen Storage Disease Type I

Glycogen Storage Disease I

Hepatorenal Form Of Glycogen Storage Disease

Hepatorenal Glycogenosis

Glucose-6-Phosphatase Deficiency

Glycogen Storage Disease, Type I

Glycogen Storage Disease Due To Glucose-6-Phosphatase Deficiency Type Ia

GSD1A

Gsd1

Von Gierke'S Disease

Glycogen Storage Disease Type 1a

Glycogen Storage Disease 1a

Glucose-6-Phosphate Transport Defect

Gsd Ia

Deficiency Of Glucose-6-Phosphatase

Glycogenosis Type I

Glucose-6-Phosphatase Deficiency Glycogen Storage Disease

Glycogenosis Type 1

Glucose-6-Phosphate Deficiency

Gsd I

Gsd Type I

G6p Deficiency Type 1a

Gsd Due To G6p Deficiency Type 1a

Gsd Due To G6p Deficiency Type Ia

Gsd Type 1a

Gsdia

Glycogen Storage Disease Due To G6p Deficiency Type Ia

Glycogenosis Due To Glucose-6-Phosphatase Deficiency Type 1a

Glycogenosis Due To Glucose-6-Phosphatase Deficiency Type Ia

Glycogenosis Type Ia

Gsd-Ia

Storage Disease, Glycogen, Type 1a

Glycogen Storage Disease Type Ia

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SLC37A3 RGD RGD:1310346
Canis familiaris SLC37A3 VGNC VGNC:46388
Mus musculus SLC37A3 MGD MGI:1919394
Felis catus SLC37A3 VGNC VGNC:80719
Bos taurus SLC37A3 VGNC VGNC:34844
Macaca mulatta SLC37A3 VGNC VGNC:81574