2. Gene
  3. Cxadr - CXADR, Ig-like cell adhesion molecule Gene

Cxadr - CXADR, Ig-like cell adhesion molecule Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Car1

Gene ID: 89843 | Gene type: protein coding

About Cxadr

Summary

Predicted to enable several functions, including PDZ domain binding activity; beta-catenin binding activity; and connexin binding activity. Predicted to be involved in several processes, including AV node cell-bundle of His cell adhesion involved in cell communication; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and neutrophil chemotaxis. Predicted to act upstream of or within negative regulation of cardiac muscle cell proliferation. Located in bicellular tight junction and neuron projection. Orthologous to human CXADR (CXADR Ig-like cell adhesion molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cxadr Products(2)

mRNA Protein Name
NM_001399207.1 NP_001386136.1 coxsackievirus and adenovirus receptor homolog isoform 1 precursor
NM_053570.2 NP_446022.1 coxsackievirus and adenovirus receptor homolog isoform 2 precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in bicellular tight junction IDA
IDA: Inferred from direct assay
12808125 RGD
located in neuron projection IDA
IDA: Inferred from direct assay
19461877 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

coxsackievirus and adenovirus receptor homolog

CAR

coxsackie virus and adenovirus receptor

rCAR

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16275 Cxadr Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS03382 CXADR Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cxadr NCBI NCBI:1525
Mus musculus Cxadr NCBI NCBI:13052