TM9SF2 - transmembrane 9 superfamily member 2 Gene

Homo sapiens

Also known as P76

Gene ID: 9375 | Gene type: protein coding

About TM9SF2

Cytogenetic location: 13q32.3 Genomic coordinates (GRCh38): 13:99,501,472-99,564,048 (from NCBI)

This gene has 6 transcripts (splice variants), 186 orthologues and 3 paralogues. Ubiquitous expression in thyroid (RPKM 79.3), colon (RPKM 75.9) and 25 other tissues.

Summary

This gene encodes a member of the transmembrane 9 superfamily. The encoded 76 kDa protein localizes to early endosomes in human cells. The encoded protein possesses a conserved and highly hydrophobic C-terminal domain which contains nine transmembrane domains. The protein may play a role in small molecule transport or act as an ion channel. A pseudogene associated with this gene is located on the X chromosome. [provided by RefSeq, Oct 2012]

TM9SF2 Products(1)

mRNA	Protein	Name
NM_004800.3	NP_004791.1	transmembrane 9 superfamily member 2 precursor

TM9SF2 Protein Structure

EMP70

0
200
400
600
663 a.a.

Protein Preferred Names

Protein Names

transmembrane 9 superfamily member 2

76 kDa membrane protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14613	TM9SF2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	TM9SF2	VGNC	VGNC:53839
Canis familiaris	TM9SF2	VGNC	VGNC:47415
Rattus norvegicus	TM9SF2	RGD	RGD:1359230
Macaca mulatta	TM9SF2	VGNC	VGNC:78568
Felis catus	TM9SF2	VGNC	VGNC:66228
Mus musculus	TM9SF2	MGD	MGI:1915309

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