CD101 - CD101 molecule Gene

Homo sapiens

Also known as V7; IGSF2; EWI-101

Gene ID: 9398 | Gene type: protein coding

About CD101

Cytogenetic location: 1p13.1 Genomic coordinates (GRCh38): 1:117,001,760-117,036,552 (from NCBI)

This gene has 5 transcripts (splice variants), 100 orthologues and 5 paralogues. Broad expression in small intestine (RPKM 2.3), lung (RPKM 2.1) and 18 other tissues.

Summary

Predicted to enable hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. Predicted to be involved in cell surface receptor signaling pathway. Predicted to act upstream of or within positive regulation of myeloid leukocyte differentiation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

CD101 Products(4)

mRNA	Protein	Name
NM_001256106.3	NP_001243035.1	immunoglobulin superfamily member 2 isoform 1 precursor
NM_001256109.3	NP_001243038.1	immunoglobulin superfamily member 2 isoform 1 precursor
NM_001256111.3	NP_001243040.1	immunoglobulin superfamily member 2 isoform 2 precursor
NM_004258.6	NP_004249.2	immunoglobulin superfamily member 2 isoform 1 precursor

CD101 Protein Structure

V-set

Ig_2

I-set

Ig_2

V-set

0
200
400
600
800
1021 a.a.

Protein Preferred Names

Protein Names

immunoglobulin superfamily member 2

cell surface glycoprotein V7

Related Diseases

Diseases

Alias

Langerhans Cell Histiocytosis

Histiocytosis X	Lch
Langerhans Cell Granulomatosis	Langerhans-Cell Histiocytosis
Letterer-Siwe Disease	Hashimoto-Pritzger Disease
Histiocytosis, Langerhans-Cell	Langerhan'S Cell Histiocytosis
Letterer-Siwe Disease Involving Intra-Abdominal Lymph Nodes	Letterer-Siwe Disease Involving Intrapelvic Lymph Nodes
Letterer-Siwe Disease Involving Intrathoracic Lymph Nodes	Letterer-Siwe Disease Involving Lymph Nodes Of Axilla And Upper Limb
Letterer-Siwe Disease Involving Lymph Nodes Of Head, Face And Neck	Letterer-Siwe Disease Involving Lymph Nodes Of Head, Face, And Neck
Letterer-Siwe Disease Involving Lymph Nodes Of Inguinal Region And Lower Limb	Letterer-Siwe Disease Involving Lymph Nodes Of Multiple Sites
Letterer-Siwe Disease Involving Spleen	Letterer-Siwe Disease Of Intra-Abdominal Lymph Nodes
Letterer-Siwe Disease Of Intrapelvic Lymph Nodes	Letterer-Siwe Disease Of Intrathoracic Lymph Nodes
Letterer-Siwe Disease Of Lymph Nodes Of Axilla And Upper Limb	Letterer-Siwe Disease Of Lymph Nodes Of Axilla And/Or Upper Limb
Letterer-Siwe Disease Of Lymph Nodes Of Head, Face And Neck	Letterer-Siwe Disease Of Lymph Nodes Of Head, Face And/Or Neck
Letterer-Siwe Disease Of Lymph Nodes Of Inguinal Region Amd/Or Lower Limb	Letterer-Siwe Disease Of Lymph Nodes Of Inguinal Region And Lower Limb
Letterer-Siwe Disease Of Lymph Nodes Of Inguinal Region And/Or Lower Limb	Letterer-Siwe Disease Of Lymph Nodes Of Multiple Sites
Letterer-Siwe Disease Of Spleen	Familial Letterer-Siwe Disease
Langerhans-Cell Histiocytosis Nos

Histiocytosis

Chronic Histiocytosis X	Hand Schuller Christian Disease
Hand-Schüller-Christian Disease	Histiocytic Syndrome
Histiocytosis, Langerhans-Cell

Median Rhomboid Glossitis

Persistent Tuberculum Impar	Glossitis Rhomboidea Mediana
Superficial Midline Glossitis

Vulvovaginal Candidiasis

Candidiasis Of Vulva And Vagina	Candidiasis, Vulvovaginal
Candidal Vulvovaginitis	Candidal: Cervix
Monilial Vulvovaginitis	Candidiasis Vulvovaginal

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-108009A	Rezafungin acetate	Inhibitor	98.15%	Yes
HY-108009	Rezafungin	Inhibitor	/	Unkown

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02187	CD101 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	CD101	VGNC	VGNC:70927
Bos taurus	CD101	VGNC	VGNC:27001
Rattus norvegicus	CD101	RGD	RGD:1311453
Canis familiaris	CD101	VGNC	VGNC:38928
Felis catus	CD101	VGNC	VGNC:67746
Mus musculus	CD101	MGD	MGI:2685862

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