CAMK2N2 - calcium/calmodulin dependent protein kinase II inhibitor 2 Gene

Homo sapiens

Also known as CAMKIIN; CAM-KIIN

Gene ID: 94032 | Gene type: protein coding

About CAMK2N2

Cytogenetic location: 3q27.1 Genomic coordinates (GRCh38): 3:184,259,213-184,261,553 (from NCBI)

This gene has 1 transcript (splice variant), 186 orthologues and 1 paralogue. Biased expression in brain (RPKM 13.3), adrenal (RPKM 4.9) and 1 other tissue.

Summary

This gene encodes a protein that is highly similar to the rat CaM-KII inhibitory protein, an inhibitor of calcium/calmodulin-dependent protein kinase II (CAMKII). CAMKII regulates numerous physiological functions, including neuronal synaptic plasticity through the phosphorylation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate (AMPA) receptors. Studies of the similar protein in rat suggest that this protein may function as a negative regulator of CaM-KII and may act to inhibit the phosphorylation of AMPA receptors. [provided by RefSeq, Jul 2008]

CAMK2N2 Products(1)

mRNA	Protein	Name
NM_033259.3	NP_150284.1	calcium/calmodulin-dependent protein kinase II inhibitor 2

CAMK2N2 Protein Structure

CaM-KIIN

0
79 a.a.

Protein Preferred Names

Protein Names

calcium/calmodulin-dependent protein kinase II inhibitor 2

CaM-KII inhibitory protein

Related Diseases

Diseases

Alias

Amyotrophic Lateral Sclerosis 21

Amyotrophic Lateral Sclerosis Type 21	ALS21
Multisystem Proteinopathy 5	Msp5
Distal Myopathy With Vocal Cord Weakness	Vcpdm
Myopathy, Distal, 2, Formerly	Mpd2, Formerly
Vocal Cord And Pharyngeal Dysfunction With Distal Myopathy, Formerly	Vcpdm, Formerly
Vocal Cord And Pharyngeal Distal Myopathy	Matr3-Related Distal Myopathy
Distal Myopathy 2	Mpd2
Vocal Cord And Pharyngeal Dysfunction With Distal Myopathy	Sclerosis, Lateral, Amyotrophic, Type 21
Myopathy, Distal 2

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01863	CAMK2N2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CAMK2N2	RGD	RGD:708411
Bos taurus	CAMK2N2	VGNC	VGNC:26724
Mus musculus	CAMK2N2	MGD	MGI:1920297
Macaca mulatta	CAMK2N2	VGNC	VGNC:70617
Canis familiaris	CAMK2N2	VGNC	VGNC:38682

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