2. Gene
  3. CCL4L2 - C-C motif chemokine ligand 4 like 2 Gene

CCL4L2 - C-C motif chemokine ligand 4 like 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as CCL4L; SCYA4L; AT744.2; SCYQ4L2

Gene ID: 9560 | Gene type: protein coding

About CCL4L2

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:36,211,063-36,212,873 (from NCBI)

This gene has 10 transcripts (splice variants), 1 gene allele, 175 orthologues and 25 paralogues. Broad expression in bone marrow (RPKM 21.9), gall bladder (RPKM 7.0) and 15 other tissues.

Summary

This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this family member is similar to the chemokine (C-C motif) ligand 4 product, which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals, where most individuals have one to five copies. This gene copy contains a non-consensus splice acceptor site at the 3' terminal exon found in Other highly similar gene copies, and it thus uses Other alternative splice sites for the 3' terminal exon, resulting in multiple transcript variants. [provided by RefSeq, Apr 2014]

CCL4L2 Products(8)

mRNA Protein Name
NM_001291468.2 NP_001278397.1 C-C motif chemokine 4-like isoform 1 precursor
NM_001291469.2 NP_001278398.1 C-C motif chemokine 4-like isoform 2 precursor
NM_001291470.2 NP_001278399.1 C-C motif chemokine 4-like isoform 2 precursor
NM_001291471.2 NP_001278400.1 C-C motif chemokine 4-like isoform 3 precursor
NM_001291472.2 NP_001278401.1 C-C motif chemokine 4-like isoform 4 precursor
NM_001291473.2 NP_001278402.1 C-C motif chemokine 4-like isoform 5 precursor
NM_001291474.2 NP_001278403.1 C-C motif chemokine 4-like isoform 6 precursor
NM_001291475.2 NP_001278404.1 C-C motif chemokine 4-like isoform 7 precursor

CCL4L2 Protein Structure

IL8

IL8: Small cytokines (intecrine/chemokine), interleukin-8 like (29 - 86)

  • 0
  • 92 a.a.
Protein Preferred Names Protein Names

C-C motif chemokine 4-like

MIP-1-beta

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02104 CCL4L2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CCL4L2 MGD MGI:98261