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  3. P2RY14 - purinergic receptor P2Y14 Gene

P2RY14 - purinergic receptor P2Y14 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as P2Y14; BPR105; GPR105

Gene ID: 9934 | Gene type: protein coding

About P2RY14

Cytogenetic location: 3q25.1 Genomic coordinates (GRCh38): 3:151,212,117-151,278,542 (from NCBI)

This gene has 3 transcripts (splice variants), 195 orthologues and 6 paralogues. Broad expression in esophagus (RPKM 4.9), placenta (RPKM 4.7) and 18 other tissues.

Summary

The product of this gene belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]

P2RY14 Products(6)

mRNA Protein Name
XM_011513340.4 XP_011511642.1 P2Y purinoceptor 14 isoform X1
XM_005247923.4 XP_005247980.1 P2Y purinoceptor 14 isoform X1
XM_005247922.4 XP_005247979.1 P2Y purinoceptor 14 isoform X1
XM_017007583.3 XP_016863072.1 P2Y purinoceptor 14 isoform X1
NM_014879.4 NP_055694.3 P2Y purinoceptor 14
NM_001081455.2 NP_001074924.1 P2Y purinoceptor 14

P2RY14 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (55 - 295)

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  • 338 a.a.
Protein Preferred Names Protein Names

P2Y purinoceptor 14

G protein coupled receptor for UDP-glucose

G-protein coupled receptor 105

P2Y(14) receptor

P2Y14 receptor

UDP-glucose receptor

purinergic receptor P2Y, G-protein coupled, 14

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09925 P2RY14 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS09926 P2ry14 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS09927 P2ry14 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta P2RY14 VGNC VGNC:75633
Rattus norvegicus P2RY14 RGD RGD:70912
Bos taurus P2RY14 VGNC VGNC:32527
Mus musculus P2RY14 MGD MGI:2155705
Canis familiaris P2RY14 VGNC VGNC:44216
Felis catus P2RY14 VGNC VGNC:64011