2. Stem Cell/Wnt
  3. Smo
  4. Glasdegib maleate

Glasdegib maleate  (Synonyms: PF-04449913 maleate)

Cat. No.: HY-16391A
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Glasdegib maleate (PF-04449913 maleate) is a potent and orally bioavailable smoothened inhibitor. Glasdegib maleate binds to human SMO (amino acids 181-787) with IC50value of 4 nM.

For research use only. We do not sell to patients.

Glasdegib maleate Chemical Structure

Glasdegib maleate Chemical Structure

CAS No. : 2030410-25-2

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Glasdegib maleate Related Antibodies

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Description

Glasdegib maleate (PF-04449913 maleate) is a potent and orally bioavailable smoothened inhibitor. Glasdegib maleate binds to human SMO (amino acids 181-787) with IC50value of 4 nM[1].

Molecular Weight

490.51

Formula

C25H26N6O5
CAS No.
SMILES

O=C(NC1=CC=C(C#N)C=C1)N[C@H]2C[C@H](C3=NC4=CC=CC=C4N3)N(C)CC2.OC(/C=C\C(O)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Glasdegib maleate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glasdegib2030410-25-2PF-04449913PF04449913PF 04449913SmoSmoothenedInhobitorSMOInhibitorinhibitorinhibit

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