2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. GpTx-1

GpTx-1 is a potent and selective NaV1.7 antagonist with an IC50 of 10 nM.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

GpTx-1 Chemical Structure

GpTx-1 Chemical Structure

CAS No. : 1661050-12-9

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GpTx-1 Related Antibodies

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Description

GpTx-1 is a potent and selective NaV1.7 antagonist with an IC50 of 10 nM[1].

IC50 & Target

IC50: 10 nM (hNaV1.7), 0.2 μM (hNaV1.4)[1]
Molecular Weight

4073.82

Formula

C176H271N53O45S7
CAS No.
Sequence

Asp-Cys-Leu-Gly-Phe-Met-Arg-Lys-Cys-Ile-Pro-Asp-Asn-Asp-Lys-Cys-Cys-Arg-Pro-Asn-Leu-Val-Cys-Ser-Arg-Thr-His-Lys-Trp-Cys-Lys-Tyr-Val-Phe-NH2 (Disulfide bridge: Cys2-Cys17;Cys9-Cys23;Cys16-Cys30)
Sequence Shortening

DCLGFMRKCIPDNDKCCRPNLVCSRTHKWCKYVF-NH2 (Disulfide bridge: Cys2-Cys17;Cys9-Cys23;Cys16-Cys30)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GpTx-1 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GpTx-11661050-12-9GpTx1GpTx 1Sodium ChannelNa channelsNa+ channelsGrammostola porteriInhibitorinhibitorinhibit

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