2. GPCR/G Protein Neuronal Signaling
  3. Neurokinin Receptor
  4. GR 64349

GR 64349 is a potent and highly selective NK2 receptor peptide antagonist, with an EC50 of 3.7 nM in rat colon. GR 64349 exhibits selectivity >1000 and >300-fold with respect to NK1 and NK3 receptors, respectively.

For research use only. We do not sell to patients.

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GR 64349 Chemical Structure

GR 64349 Chemical Structure

CAS No. : 137593-52-3

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Based on 1 publication(s) in Google Scholar

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Description

GR 64349 is a potent and highly selective NK2 receptor peptide antagonist, with an EC50 of 3.7 nM in rat colon. GR 64349 exhibits selectivity >1000 and >300-fold with respect to NK1 and NK3 receptors, respectively[1][2].

Molecular Weight

921.11

Formula

C42H68N10O11S
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Lys-Asp-Ser-Phe-Val-{Aaa}-Leu-Met-NH2
Sequence Shortening

KDSFV{Aaa}LM-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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GR 64349 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GR 64349137593-52-3GR64349GR-64349Neurokinin ReceptorNK receptorTachykinin receptorInhibitorinhibitorinhibit

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