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  3. GSK-1562590

GSK-1562590 is a uropeptide-II receptor antagonist with high affinity and selectivity. GSK-1562590 exhibits significant antagonistic activity in multiple bioassays and, in contrast, displays relatively sustained receptor binding times. GSK-1562590 can inhibit human urinary peptide-II-induced aortic contraction in rats in experiments, and its effect can last for at least 24 hours.

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GSK-1562590 Chemical Structure

GSK-1562590 Chemical Structure

CAS No. : 1003877-55-1

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Description

GSK-1562590 is a uropeptide-II receptor antagonist with high affinity and selectivity. GSK-1562590 exhibits significant antagonistic activity in multiple bioassays and, in contrast, displays relatively sustained receptor binding times. GSK-1562590 can inhibit human urinary peptide-II-induced aortic contraction in rats in experiments, and its effect can last for at least 24 hours[1].

Molecular Weight

581.49

Formula

C30H30Cl2N4O4

CAS No.
SMILES

NC(C1=CC=CC(C(C=C2)=CC=C2[C@H](CN3CCCC3)N(C)C(CN4C5=CC(Cl)=C(Cl)C=C5OCC4=O)=O)=C1)=O

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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GSK-1562590 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
GSK-1562590
Cat. No.:
HY-167688
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