2. Anti-infection
  3. HCV
  4. GSK8175

GSK8175 is a non-nucleoside polymerase (NS5B) inhibitor of hepatitis C virus (HCV). GSK8175 is a sulfonamide- N-benzoxaborole analog with low in vivo clearance across preclinical species and broad-spectrum activity against HCV replicons.

For research use only. We do not sell to patients.

GSK8175 Chemical Structure

GSK8175 Chemical Structure

CAS No. : 1423007-82-2

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GSK8175 Related Antibodies

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Description

GSK8175 is a non-nucleoside polymerase (NS5B) inhibitor of hepatitis C virus (HCV). GSK8175 is a sulfonamide- N-benzoxaborole analog with low in vivo clearance across preclinical species and broad-spectrum activity against HCV replicons[1].

Clinical Trial
Molecular Weight

568.81

Formula

C27H23BClFN2O6S
CAS No.
SMILES

O=C(C1=C(C(C=C2)=CC=C2F)OC3=CC(N(C4=CC(Cl)=C5C(COB5O)=C4)[S](C)(=O)=O)=C(C6CC6)C=C13)NC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GSK8175 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GSK81751423007-82-2GSK2878175GSK 8175GSK-8175GSK 2878175GSK-2878175HCVHepatitis C virusnon-nucleoside polymeraseNS5Bbroad-spectrumHCV repliconsInhibitorinhibitorinhibit

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