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  5. Guineesine

Guineesine can be isolated from Piper longum L.

For research use only. We do not sell to patients.

Guineesine Chemical Structure

Guineesine Chemical Structure

CAS No. : 55038-30-7

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Description

Guineesine can be isolated from Piper longum L[1].

Cellular Effect
Cell Line Type Value Description References
THP-1 IC50
> 50 μg/mL
Compound: 1
Inhibition of sICAM1/LFA1 interaction-mediated human THP1 cell adhesion after 1 hr by ELISA
Inhibition of sICAM1/LFA1 interaction-mediated human THP1 cell adhesion after 1 hr by ELISA
[PMID: 18672369]
U-937 EC50
290 nM
Compound: 67
Inhibition of [14C]-AEA uptake in human U937 cells preincubated for 15 mins followed by [14C]-AEA addition and measured after 5 mins by scintillation counting method
Inhibition of [14C]-AEA uptake in human U937 cells preincubated for 15 mins followed by [14C]-AEA addition and measured after 5 mins by scintillation counting method
[PMID: 30816712]
Molecular Weight

383.52

Formula

C24H33NO3

CAS No.
SMILES

O=C(/C=C/C=C/CCCCCC/C=C/C1=CC=C2OCOC2=C1)NCC(C)C

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Guineesine
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HY-121205
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