2. Cell Cycle/DNA Damage Epigenetics
  3. Sirtuin
  4. Guttiferone G

Guttiferone G inhibits recombinant human SIRT1 and SIRT2 (IC50: 9 and 22 μM, respectively). Guttiferone G is weakly cytotoxic in A2780 human ovarian cell line (IC50: 8.0 μg/mL). Guttiferone G can be isolated from Garcinia macrophylla.

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Guttiferone G Chemical Structure

Guttiferone G Chemical Structure

CAS No. : 666174-75-0

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Guttiferone G Related Antibodies

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Description

Guttiferone G inhibits recombinant human SIRT1 and SIRT2 (IC50: 9 and 22 μM, respectively). Guttiferone G is weakly cytotoxic in A2780 human ovarian cell line (IC50: 8.0 μg/mL). Guttiferone G can be isolated from Garcinia macrophylla[1][2].

IC50 & Target

IC50: 9 and 22 μM (SIRT1/2)[1]
Molecular Weight

670.92

Formula

C43H58O6
CAS No.
SMILES

C/C(C)=C/C[C@](C([C@]12C/C=C(C)/C)=O)(C(C(C(C(C=C3)=CC(O)=C3O)=O)=C1O)=O)[C@](C)([C@@H](C2)C/C=C(C)/CC/C=C(C)/C)CC/C=C(C)/C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Guttiferone G Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Guttiferone G666174-75-0SirtuinOvariancytotoxicA2780Inhibitorinhibitorinhibit

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