2. Metabolic Enzyme/Protease
  3. Carbonic Anhydrase
  4. hCAIX/XII-IN-11

hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII with a Ki value of 0.7 μM for both the isoforms. hCAIX/XII-IN-11 can be used for anticancer research.

For research use only. We do not sell to patients.

hCAIX/XII-IN-11 Chemical Structure

hCAIX/XII-IN-11 Chemical Structure

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hCAIX/XII-IN-11 Related Antibodies

Top Publications Citing Use of Products

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CA CA I CA Ⅱ CA Ⅸ CA XII

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Description

hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII with a Ki value of 0.7 μM for both the isoforms. hCAIX/XII-IN-11 can be used for anticancer research[1].

IC50 & Target[1]

hCA XII

0.7 μM (Ki)

hCA IX

0.7 μM (Ki)

In Vitro

hCAIX/XII-IN-11 shows cytotoxic activity against A549 lung cancer cells, with IC50 value of 81 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

hCAIX/XII-IN-11 Related Antibodies
Molecular Weight

291.23

Formula

C13H10FN3O4
SMILES

CC1=C(N=NN1C2=CC=C(C=C2)F)C(/C=C(C(O)=O)\O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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hCAIX/XII-IN-11 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

hCAIX/XII-IN-11Carbonic AnhydraseCarbonate dehydrataseanticancerA549Inhibitorinhibitorinhibit

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